Category: 696-59-3

The author of 《Unexpected activated carbon-catalyzed pyrrolo[1,2-a]quinoxalines synthesis in water》 were Sun, Qi; Liu, Liyan; Yang, Yu; Zha, Zhenggen; Wang, Zhiyong. And the article was published in Chinese Chemical Letters in 2019. Application In Synthesis of 2,5-Dimethoxytetrahydrofuran The author mentioned the following in the article:

An interesting and recyclable activated carbon/water catalytic system for efficient synthesis of pyrrolo[1,2-a]quinoxaline derivatives was developed. The intramol. C-N and C-C bond was easily constructed in water under mild condition. This reaction featured a broad substrate scope, a good tolerance to water and air, metal-free, additive-free and redox reagent-free. In the part of experimental materials, we found many familiar compounds, such as 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Application In Synthesis of 2,5-Dimethoxytetrahydrofuran)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Application In Synthesis of 2,5-Dimethoxytetrahydrofuran

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Tian, Run; Liang, Zhi-Qun; Wang, Yong; Zeng, Nian-Kai published an article in 2022. The article was titled 《Analysis of aromatic components of two edible mushrooms, Phlebopus portentosus and Cantharellus yunnanensis using HS-SPME/GC-MS》, and you may find the article in Results in Chemistry.COA of Formula: C6H12O3 The information in the text is summarized as follows:

A headspace solid-phase microextraction (HS-SPME) coupled with gas chromatog.-mass spectrometry (GC-MS) was used to evaluate the profile of the volatile components that accounted for the aroma of two edible mushrooms, viz. Phlebopus portentosus and Cantharellus yunnanensis. There were 51 and 69 volatile compounds identified from P. portentosus and C. yunnanensis, resp. These compounds were mainly acids, hydrocarbons, ketones, esters, aldehydes, and alcs., of which acetic acid was most abundant among these volatile components. Onanoic acid, 9-oxo-, Me ester, 2-pentyl-furan, and 5, 6-dihydro-2-pyranone were discovered in the mushrooms for the first time, and the volatile compounds of C. yunnanensis was also investigated for the first time. In addition, the volatile compounds of P. portentosus and C. yunnanensis were analyzed by principal components anal. (PCA). The findings reveal the differences among samples and provide the basic data for the chemotaxonomy in studying P. portentosus and C. yunnanensis. The experimental part of the paper was very detailed, including the reaction process of 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3COA of Formula: C6H12O3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.COA of Formula: C6H12O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Willkomm, Janina; Bouzidi, Sara; Bertin, Erwan; Birss, Viola I.; Piers, Warren E. published their research in ACS Catalysis in 2021. The article was titled 《Aqueous CO2 Reduction by a Re(bipyridine)-polypyrrole Film Deposited on Colloid-Imprinted Carbon》.Name: 2,5-Dimethoxytetrahydrofuran The article contains the following contents:

Herein, we report a [Re(bipyridine)]-carbon hybrid material for efficient and selective CO2 to CO conversion in water. The Re catalyst was incorporated into a nanoporous colloid-imprinted carbon (CIC) powder by an electrochem. polymerization method. Uniform [Re(bipyridine)]-containing polymer films were formed on the carbon surface, where the catalyst-polymer loading could be controlled by varying the polymerization parameters. Thorough pre- and post-catalysis characterization confirmed the integrity of the [Re(bpy)] CO2 reduction catalyst. CIC|poly[Re] electrodes reduced CO2 to CO in 0.5 M CO2-saturated KHCO3 electrolyte solution at Eappl. = -0.66 V vs. reversible hydrogen electrode (RHE) (η = 550 mV), with initial Faradaic efficiencies for CO formation (FECO) between 88 and 100%. Higher catalyst loadings generally yielded higher FECO and better long-term stability under catalytic conditions, producing CO and maintaining selectivity of above 70% for a period of at least 24 h for the hybrid material with the highest [Re(bipyridine)] polymer loading. While electrochem. analyses suggested some electron and mass transport issues on shorter timescales, these were not confirmed in long-term electrolysis. Our work highlights the great applicability of (electro)polymerization techniques in combination with nanoporous CIC to prepare hybrid materials for energy conversion.2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Name: 2,5-Dimethoxytetrahydrofuran) was used in this study.

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Name: 2,5-Dimethoxytetrahydrofuran

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Nicolai, Alice; Madia, Valentina Noemi; Messore, Antonella; De Vita, Daniela; De Leo, Alessandro; Ialongo, Davide; Tudino, Valeria; Tortorella, Elisabetta; Scipione, Luigi; Taurone, Samanta; Pergolizzi, Tiziano; Artico, Marco; Di Santo, Roberto; Costi, Roberta; Scarpa, Susanna published their research in Pharmaceuticals in 2021. The article was titled 《Anti-tumoral effects of a (1H-pyrrol-1-yl)methyl-1Hbenzoimidazole carbamate ester derivative on head and neck squamous carcinoma cell lines》.Product Details of 696-59-3 The article contains the following contents:

Nocodazole is an antineoplastic agent that exerts its effects by depolymerizing microtubules. Herein we report a structural analog of nocodazole, a (1H-pyrrol-1-yl)methyl-1H-benzoimidazole carbamate ester derivative, named RDS 60. We evaluated the antineoplastic properties of RDS 60 in two human head and neck squamous cell carcinoma (HNSCC) cell lines and we found that this compound significantly inhibited replication of both HNSCC cell lines without inducing any important cytotoxic effect on human dermal fibroblasts and human keratinocytes. The treatment of HNSCC cell lines with 1 μM RDS 60 for 24 h stopped development of normal bipolar mitotic spindles and, at the same time, blocked the cell cycle in G2/M phase together with cytoplasmic accumulation of cyclin B1. Consequently, treatment with 2 μM RDS 60 for 24 h induced the activation of apoptosis in both HNSCC cell lines. Addnl., RDS 60 was able to reverse the epithelial-mesenchymal transition and to inhibit cell migration and extracellular matrix infiltration of both HNSCC cell lines. The reported results demonstrate that this compound has a potent effect in blocking cell cycle, inducing apoptosis and inhibiting cell motility and stromal invasion of HNSCC cell lines. Therefore, the ability of RDS 60 to attenuate the malignancy of tumor cells suggests its potential role as an interesting and powerful tool for new approaches in treating HNSCC. In the part of experimental materials, we found many familiar compounds, such as 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Product Details of 696-59-3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Product Details of 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

In 2022,Gao, Anjiang; Wang, Yao; Lin, Guiying; Li, Bin; Hu, Xun; Huang, Yong; Zhang, Shu; Zhang, Hong published an article in Renewable Energy. The title of the article was 《Volatile-char interactions during biomass pyrolysis: Reactor design toward product control》.Category: tetrahydrofurans The author mentioned the following in the article:

This paper proposes a novel reactor featuring controllable adjustment of volatile-char interactions to investigate the pyrolysis of poplar wood and corresponding products. Controllable adjustment of volatile-char interactions enables the selective production of pyrolysis products. The oxygen content in biochar nearly disappears with the reduction of volatile-char interactions and the pore structure of biochar is improved after the interactions being intensified. Moreover, as the interactions reduce, the bio-oil yield increases by 1.23 times, and the outputs of acetic acid and phenols in the bio-oil exhibit decreasing trends, while that of levoglucosan is improved by nearly 4.5 times. Furthermore, the average mol. weight of bio-oil decreases from 786 to 322 g/mol with the continuous intensification of volatile-char interactions. It concludes that the controllable adjustment of volatile-char interactions plays a vital role in regulating the distribution of pyrolysis products and is of great importance to the production of light oil.2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Category: tetrahydrofurans) was used in this study.

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Category: tetrahydrofurans

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Yang, Yi-Lin; Li, Shen; Zhang, Fa-Guang; Ma, Jun-An published their research in Organic Letters in 2021. The article was titled 《N-Iodosuccinimide-Promoted [3 + 2] Annulation Reaction of Aryldiazonium Salts with Guanidines to Construct Aminotetrazoles》.Related Products of 696-59-3 The article contains the following contents:

A N-iodosuccinimide (NIS) -promoted [3+2] annulation reaction of aryldiazonium salts ArN2BF4 (Ar = 4-chlorophenyl, naphthalen-2-y, 3-methoxyphenyl, etc.) with guanidines RNHC(=NHHCl)NH2 (R = H, Me, Boc, 4-cyanophenyl, etc.) has been developed for the construction of previously elusive 2-aryl-5-amino-2H-tetrazoles I. This transformation takes advantage of readily available starting materials, proceeds under metal-free, mild and robust conditions, and holds broad functional group compatibility. The utility of this protocol is further manifested via coupling, annulation, deamination, and denitrogenation derivatizations. In the experiment, the researchers used many compounds, for example, 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Related Products of 696-59-3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Related Products of 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Rahmatpour, Ali; Sajjadinezhad, Seyed Mehrzad; Mirkani, Ahmad; Notash, Behrouz published their research in Tetrahedron in 2021. The article was titled 《Regioselective synthesis of di-aromatic ring-fused 2,8-dioxa/dithia bicyclo[3.3.1]nonane derivatives via recyclable polymeric Bronsted acid-catalyzed one-pot tandem formation of multiple chemical C-C/C-O and C-C/C-S bonds》.Application of 696-59-3 The article contains the following contents:

An environmentally benign and straightforward synthetic approach for the assembly of a new class of diverse sym. substituted di-aromatic-fused 2,8-dioxa/dithiabicyclo[3.3.1]nonane derivatives containing methylene-bridged bicyclic framework via reusable cross-linked polystyrene-supported p-toluenesulfonic acid-catalyzed tandem reactions of substituted phenols/selected thiophenol with 1,1,3,3-tetramethoxypropane under neat conditions has been reported in which four new chem. bonds (two C-C/two C-O)-(two C-C/two C-S), two new six-membered cycles, and two new stereogenic tertiary carbon centers were constructed in a single operation. The synthetic utility of this method was also demonstrated. In addition, this present protocol could be successfully extended to the selected naphthols and dihydroxynaphthalenes as the enol partner of phenols with high efficiency. The developed transformation featured high efficiency, the use of com. accessible feedstocks, excellent regioselectivity, simple operation, gram-scale synthesis, and good functional group compatibility. Furthermore, the solvent-free conditions, easily recoverable catalyst, and efficient recycling render the protocol green, economic and sustainable. After reading the article, we found that the author used 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Application of 696-59-3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Application of 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

《Towards the preparation of stable cyclic amino(ylide)carbenes》 was published in Molecules in 2020. These research results belong to Steinert, Henning; Schwarz, Christopher; Kroll, Alexander; Gessner, Viktoria H.. HPLC of Formula: 696-59-3 The article mentions the following:

The exptl. and computational studies on the synthesis and stability of CAYCs based on pyrroles with trialkyl onium groups was described. Attempts to isolate two CAYCs with trialkyl phosphonium and sulfonium ylides resulted in the deprotonation of the alkyl groups instead of the formation of the desired CAYCs. In case of the PCy3-substituted system, the corresponding ylide was isolated, while deprotonation of the SMe2-functionalized compound led to the formation of ethene and the thioether. Detailed computational studies on various trialkyl onium groups showed that both the α- and β-deprotonated compounds were energetically favored over the free carbene. The most stable candidates were revealed to be α-hydrogen-free adamantyl-substituted onium groups, for which β-deprotonation was less favorable at the bridgehead position. Overall, the calculations showed that the isolation of CAYCs should be possible, but careful design was required to exclude decomposition pathways such as deprotonations at the onium group. In the experimental materials used by the author, we found 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3HPLC of Formula: 696-59-3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.HPLC of Formula: 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Synthetic Route of C6H12O3In 2022 ,《Microwave-Assisted Synthesis, Biological Activity Evaluation, Molecular Docking, and ADMET Studies of Some Novel Pyrrolo [2,3-b] Pyrrole Derivatives》 appeared in Molecules. The author of the article were Kamel, Moumen S.; Belal, Amany; Aboelez, Moustafa O.; Shokr, E. Kh.; Abdel-Ghany, H.; Mansour, Hany S.; Shawky, Ahmed M.; El-Remaily, Mahmoud Abd El Aleem Ali Ali. The article conveys some information:

Novel pyrrolo [2,3-b] pyrrole derivatives were synthesized and their hypolipidemic activity was assessed in hyperlipidemic rats. The chem. structures of the new derivatives were confirmed through spectral anal. Compounds I and II were revealed to be the most effective hypolipidemic agents, with considerable hypocholesterolemic and hypotriglyceridemic effects. They appear to be promising candidates for creating new powerful derivatives with anti-atherosclerotic and hypolipidemic properties. As for antimicrobial activity, some of the tested compounds showed moderate activity against Pseudomonas aeruginosa: compound II revealed an MIC value of 50μg/mL, compared to 25μg/mL for ciprofloxacin. Compound III showed good antimicrobial activity against Staphylococcus aureus, comparable to ciprofloxacin, and roughly half the activity of ampicillin, according to MIC values. Compound IV has an MIC approx. 25% of that of clotrimazole against Candida albicans. Compound IV also showed the highest antioxidant activity with 59% inhibition of radical scavenging activity. Addnl., the cytotoxic activity of these new derivatives was investigated and most of them showed good anticancer activity against the three tested cell lines. In the experiment, the researchers used 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Synthetic Route of C6H12O3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Synthetic Route of C6H12O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Synthetic Route of C6H12O3In 2019 ,《Synthesis of N-substituted pyrrole derivatives via indium-assisted one-pot reduction/N-annulation sequence reaction》 appeared in Heterocycles. The author of the article were Kim, Eungyung; Jeong, Mingyeong; Lee, Hyejeong; Kim, Byeong Hyo. The article conveys some information:

A synthesis strategy toward diverse pyrrole derivatives I (R = n-pentyl, cyclohexyl, 2-chlorophenyl, quinolin-5-yl, etc.) via an indium-mediated one-pot reductive N-annulation reaction has been developed. This protocol provides easy access to versatile N-substituted pyrroles I in the presence of an indium/AcOH co-activation promotor, with excellent yields. The experimental process involved the reaction of 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Synthetic Route of C6H12O3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Synthetic Route of C6H12O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem