Category: 696-59-3

Product Details of 696-59-3In 2020 ,《Rearrangement and cyclisation reactions on the 1-arylpyrrol-2-iminyl-2-aryliminopyrrol-1-yl radical energy surface》 appeared in ARKIVOC (Gainesville, FL, United States). The author of the article were Borthwick, Scott; Foot, Jonathan; Ieva, Maria; McNab, Hamish; McNab, Lilian; Rozgowska, Emma J.; Wright, Andrew. The article conveys some information:

Independent generation of iminyl and pyrrol-1-yl radicals by flash vacuum pyrolysis of oxime ether I (X = N; R1 = MeO; R2 = 4-MeC6H4) and imine I (X = N; R1 = 4-MeC6H4; R2 = Me2N), resp., provided two regioisomeric pyrrolo[1,2-a]quinoxalines II. This shows that radical species interconvert via spirodienyl moiety at high temperatures Corresponding generation of pyrrol-1-yl radical from I (X = CH; R1 = 4-MeC6H4; R2 = Me2N) gave single pyrrolo[1,2-α]quinoline regioisomer as the only cyclized product. In this case, DFT calculations suggested that direct cyclization of pyrrol-1-yl took place, rather than formation of spirodienyl species and exclusive migration of C-N bond. In the experimental materials used by the author, we found 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Product Details of 696-59-3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Product Details of 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

In 2022,EFSA Panel on Food Additives and Flavourings; Younes, Maged; Aquilina, Gabriele; Castle, Laurence; Engel, Karl-Heinz; Fowler, Paul J.; Frutos Fernandez, Maria Jose; Fuerst, Peter; Gundert-Remy, Ursula; Guertler, Rainer; Husoey, Trine; Manco, Melania; Moldeus, Peter; Passamonti, Sabina; Shah, Romina; Waalkens-Berendsen, Ine; Wolfle, Detlef; Wright, Matthew; Benigni, Romualdo; Bolognesi, Claudia; Cordelli, Eugenia; Chipman, Kevin; Degen, Gisela; Noerby, Karin; Svendsen, Camilla; Carfi, Maria; Martino, Carla; Tard, Alexandra; Vianello, Giorgia; Mennes, Wim published an article in EFSA Journal. The title of the article was 《Scientific opinion on Prosmoke BW 01》.HPLC of Formula: 696-59-3 The author mentioned the following in the article:

The EFSA Panel on Food Additives and Flavorings (FAF) was requested to evaluate the safety of Prosmoke BW 01 as a new smoke flavoring primary product, in accordance with Regulation (EC) No 2065/2003. Prosmoke BW01 is produced by pyrolysis of beechwood (Fagus sylvatica L.) sawdust. Its water content is estimated at 56 wt%, the total identified volatile fraction accounts for 28 wt% of the primary product, corresponding to 64% of the solvent-free mass, while the unidentified fraction amounts to 16 wt% of the primary product. Anal. data provided for three batches demonstrated that their batch-to-batch-variability was sufficiently low. However, for the batch used for the toxicol. studies, there were substantial deviations in the concentration of nearly all the constituents compared to the other three batches. The dietary exposure of Prosmoke BW 01 was estimated to be between 6.2 and 9.2 mg/kg body weight (bw) per day, resp., using SMK-EPIC and SMK-TAMDI. Using the FAIM tool, the 95th percentile exposure estimates ranged from 3.2 mg/kg bw per day for the elderly to 17.9 mg/kg bw per day for children. The Panel noted that furan-2(5H)-one is present in all batches of the primary product at an average concentration of 0.88 wt%. This substance was evaluated by the FAF Panel as genotoxic in vivo after oral exposure. The Panel considered that the (geno)toxicity studies available on the whole mixture were not adequate to support the safety assessment, due to limitations in these studies and because they were performed with a batch which may not be representative for the material of commerce. Considering that the exposure estimates for furan-2(5H)-one are above the TTC value of 0.0025 μg/kg bw per day (or 0.15 μg/person per day) for DNA-reactive mutagens and/or carcinogens, the Panel concluded that Prosmoke BW 01 raises a concern with respect to genotoxicity. In the experiment, the researchers used many compounds, for example, 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3HPLC of Formula: 696-59-3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.HPLC of Formula: 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

In 2022,Schafer, Michael; Stuenkel, Timo; Daniliuc, Constantin G.; Gilmour, Ryan published an article in Angewandte Chemie, International Edition. The title of the article was 《Regio- and Enantioselective Intermolecular Aminofluorination of Alkenes via Iodine(I)/Iodine(III) Catalysis》.Recommanded Product: 696-59-3 The author mentioned the following in the article:

The regio- and enantio-selective, intermol. vicinal fluoroamination of α-trifluoromethyl styrenes was achieved by enantioselective II/IIII catalysis. Leveraging C2-sym. resorcinol-based aryl iodide catalysts, it was possible to intercept the transient iodonium intermediate using simple nitriles, which function as both the solvent and nucleophile. In situ Ritter reaction provides direct access to the corresponding amides (up to 89% yield, e.r. 93 : 7). This main group catalysis paradigm inverts the intrinsic regioselectivity of the uncatalyzed process, thereby providing facile access to tertiary, benzylic stereocenters bearing both CF3 and F groups. Privileged phenethylamine pharmacophores was generated in which there is complete local partial charge inversion (CF3δ-/Fδ- vs. CH3δ+/Hδ+). Crystallog. analyses of representative β-fluoroamide products reveal highly pre-organized conformations that manifest the stereoelectronic gauche effect. The experimental process involved the reaction of 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Recommanded Product: 696-59-3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Recommanded Product: 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Product Details of 696-59-3In 2019 ,《Driving Recursive Dehydration by PIII/PV Catalysis: Annulation of Amines and Carboxylic Acids by Sequential C-N and C-C Bond Formation》 appeared in Journal of the American Chemical Society. The author of the article were Lecomte, Morgan; Lipshultz, Jeffrey M.; Kim-Lee, Shin-Ho; Li, Gen; Radosevich, Alexander T.. The article conveys some information:

Pyrrolylanilines such as I, pyrrolylbenzylamines, and arylethylamines underwent chemoselective tandem condensation and cyclocondensation reactions with carboxylic acids such as RCO2H mediated by di-Et bromomalonate or di-Et bromo(methyl)malonate and phenylsilane or diphenylsilane in the presence of a hexamethylphosphetane oxide to yield pyrroloquinoxaline such as II [R = MeOCH2, n-Pr, H2C:CHCH2CH2, Ph, 2-MeC6H4, 3-MeC6H4, 4-ClC6H4, 4-FC6H4, 4-MeOC6H4, PhCH2SCH2, TsNHCH2, Br(CH2)5, 3-chloro-1-cyclobutyl], pyrrolobenzodiazepines, a dihydro-β-carboline, and dihydroisoquinolines. The method was also used for Bischler-Napieralski cyclocondensations of aralkyl amides. A bromophosphonium bromide was generated as the key intermediate. A PIII/PV redox catalyst enabled iterative redox-neutral transformations complementary to reactions using the reductive driving force of the PIII/PV couple. In the experiment, the researchers used many compounds, for example, 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Product Details of 696-59-3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Product Details of 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

《Pseudo-5-Fold-Symmetrical Ligand Drives Geometric Frustration in Porous Metal-Organic and Hydrogen-Bonded Frameworks》 was written by Haase, Frederik; Craig, Gavin A.; Bonneau, Mickaele; Sugimoto, Kunihisa; Furukawa, Shuhei. Application In Synthesis of 2,5-Dimethoxytetrahydrofuran And the article was included in Journal of the American Chemical Society in 2020. The article conveys some information:

Reticular framework materials thrive on designability, but unexpected reaction outcomes are crucial in exploring new structures and functionalities. By combining “”incompatible”” building blocks, we employed geometric frustration in reticular materials leading to emergent structural features. The combination of a pseudo-C5-sym. organic building unit based on a pyrrole core with a C4-sym. copper paddlewheel synthon led to three distinct frameworks by tuning the synthetic conditions. The frameworks show structural features typical for geometric frustration: self-limiting assembly, internally stressed equilibrium structures, and topol. defects in the equilibrium structure, which manifested in formation of a hydrogen-bonded framework, distorted and broken secondary building units, and dangling functional groups, resp. The influence of geometric frustration on the CO2 sorption behavior and the discovery of a new secondary building unit shows geometric frustration can serve as a strategy to obtain highly complex porous frameworks.2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Application In Synthesis of 2,5-Dimethoxytetrahydrofuran) was used in this study.

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Application In Synthesis of 2,5-Dimethoxytetrahydrofuran

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

The author of 《Photochemical synthesis of π-extended ullazine derivatives as new electron donors for efficient conjugated D-A polymers》 were Miao, Dandan; Aumaitre, Cyril; Morin, Jean-Francois. And the article was published in Journal of Materials Chemistry C: Materials for Optical and Electronic Devices in 2019. Reference of 2,5-Dimethoxytetrahydrofuran The author mentioned the following in the article:

We report the synthesis of π-extended ullazine derivatives annulated with either electron-poor pyridine or electron-rich thiophene units through a metal-free, photochem. cyclodehydrochlorination (CDHC) reaction. The strongest electron-donor derivative, 7-tetradecylthieno[3′,2′:7,8]indolizino[6,5,4,3-ija]thieno[2,3-c]quinolone, was copolymerized with electron-deficient thienopyrroledione (TPD), isoindigo (IID), and diketopyrrolopyrrole (DPP) derivatives to provide three donor-acceptor conjugated polymers (D-A CPs). Their photophys., electrochem. and photovoltaic (PV) properties were investigated. The polymers showed broad UV-vis-NIR absorption bands with λmax values of 612 nm, 698 nm, 788 nm in chloroform and exhibited optical bandgap (Eoptg) of 1.58 eV, 1.41 eV, 1.24 eV measured as films. Inverted bulk heterojunction polymer solar cells (BHJ-PSCs) were fabricated using these polymers as host and light-harvesting materials. The device based on P3:PC70BM blends shows the best power conversion efficiency (PCE) of 2.23% (Voc = 0.55 V, Jsc = 7.86 mA cm-2, FF = 52%). These promising results demonstrate that π-extended ullazine derivatives can be used as electron-rich building blocks for the construction of D-A CPs for efficient PSCs applications. The results came from multiple reactions, including the reaction of 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Reference of 2,5-Dimethoxytetrahydrofuran)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Reference of 2,5-Dimethoxytetrahydrofuran

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

The author of 《Fluorinated iminophosphonates bearing stereodirecting phenylethyl group in synthesis of biorelevant scalemic aminophosphonates》 were Stanko, Oleg V.; Rassukana, Yuliya V.; Onys’ko, Petro P.. And the article was published in Phosphorus, Sulfur and Silicon and the Related Elements in 2019. Recommanded Product: 2,5-Dimethoxytetrahydrofuran The author mentioned the following in the article:

Diastereoselective reduction of α-(poly)fluoroalkylated iminophosphonates, bearing stereodirecting phenylethyl group at the nitrogen atom, produces diastereomeric N-(α-phenylethyl) polyfluoroalkylphosphonates. Separation and N-deprotection affords (S) and (R) α-amino polyfluoroalkylphosphonates. The latter react with 2,5-dimethoxytetrahydrofuran to give optically pure polyfluoroalkylphosphonates incorporating 1-pyrrolyl group in α-position. The results came from multiple reactions, including the reaction of 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Recommanded Product: 2,5-Dimethoxytetrahydrofuran)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Recommanded Product: 2,5-Dimethoxytetrahydrofuran

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Formula: C6H12O3In 2022 ,《A solvent-free manganese(II) -catalyzed Clauson-Kaas protocol for the synthesis of N-aryl pyrroles under microwave irradiation》 appeared in Journal of Heterocyclic Chemistry. The author of the article were Rohit, Kizhakkekuttu Radhakrishnan; Meera, Gopinadh; Anilkumar, Gopinathan. The article conveys some information:

The first manganese-catalyzed modified Clauson-Kaas reaction for N-substituted pyrroles I (R = Ph, 2-bromo-4-methylphenyl, 1,3-benzothiazol-2-yl, etc.) synthesis using 2,5-dimethoxytetrahydrofuran with variously substituted aromatic amines RNH2 has been developed (up to 89% yield). This interesting neat strategy is free from additives including co-catalysts, ligands, and acids. Relatively low cost, environmentally benign, and handy Mn(NO3)2.4H2O is employed as the catalyst under microwave conditions with a very short reaction time (20 min). The above qualities attest to the green nature of this reaction. In the part of experimental materials, we found many familiar compounds, such as 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Formula: C6H12O3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Formula: C6H12O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

In 2019,Bulletin of the Chemical Society of Ethiopia included an article by Gullapelli, Kumaraswamy; Brahmeshwari, G.; Ravichander, M.. HPLC of Formula: 696-59-3. The article was titled 《A facile synthesis of 1-aryl pyrroles by Clauson-Kaas reaction using oxone as a catalyst under microwave irradiation》. The information in the text is summarized as follows:

A new and efficient methodol. to synthesize N-substituted pyrrole derivatives I (R = Ph, 4-chloro-2-nitrophenyl, benzenesulfonyl, etc.) by Clauson-Kaas reaction employing oxone as catalyst was developed. The transformation was performed in acetonitrile under microwave irradiation This procedure has several advantages such as high yield, clean product formation, and short reaction time.2,5-Dimethoxytetrahydrofuran(cas: 696-59-3HPLC of Formula: 696-59-3) was used in this study.

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.HPLC of Formula: 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Wang, Yinghao; Wang, Yongxing; Lu, Yaowei; Cao, Qiue; Fang, Wenhao published an article in 2021. The article was titled 《Efficient hydrogenation of 5-hydroxymethylfurfural using a synergistically bimetallic Ru-Ir/C catalyst》, and you may find the article in Chemical Communications (Cambridge, United Kingdom).Computed Properties of C6H12O3 The information in the text is summarized as follows:

Activated charcoal-dispersed Ru-Ir alloy nanoparticles (ca. 2.2 nm) are a selective and reusable hydrogenation catalyst for the conversion of 5-hydroxymethylfurfural to valuable liquid biofuel. A 99% yield to 2,5-dimethylfuran is achieved at only 120°C. An acceleration in the reduction of substrate and intermediates is observed due to the synergistic effect between the Ru and Ir species. In the experimental materials used by the author, we found 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Computed Properties of C6H12O3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Computed Properties of C6H12O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem