Category: 696-59-3

HPLC of Formula: 696-59-3In 2020 ,《A Reductive Supramolecular Hydrogel: A Platform for Facile Fabrication of Diverse Metal-Nanoparticle-Decorated Conductive Networks with Spatiotemporal Control》 appeared in ChemPlusChem. The author of the article were Wang, Peng; He, Guokang; Ji, Jingwei; Li, Jian; Zhou, Kang; Tian, Li; Feng, Kai; Sun, Fuwei; Li, Guangtao. The article conveys some information:

Nanoparticle-hydrogel hybrid composites have a great potential for a broad range of applications, such as antibacterial materials, stimuli-responsive materials and catalysis. A novel supramol. hydrogel system was developed using an amino acid based amphiphile containing a terminal pyrrole moiety as a gelator. The pyrrole moiety could serve as both reducing agent and monomer, and a variety of metal precursors penetrating into the hydrogel could be reduced in situ into metal nanoparticles while the pyrrole moieties preorganized in hydrogel were oxidized into polyprroles, affording metal-nanoparticle-decorated covalent conductive networks. This strategy allows the facile fabrication of diverse mono- or multimetallic nanoparticle-polymer networks from one hydrogel by a simple reaction-diffusion approach. More importantly, besides homogeneous composites, unique multisegment heterogeneous systems with spatiotemporal control were also easily accessible. Furthermore, based on the same multifunctional mol., the fabrication of hierarchically pore-structured metal-nanoparticles-polymers as well as metal-nanoparticles-carbon structures was also realized. In addition to this study using 2,5-Dimethoxytetrahydrofuran, there are many other studies that have used 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3HPLC of Formula: 696-59-3) was used in this study.

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.HPLC of Formula: 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Li, Ziting; Cui, Shisheng; Yu, Jiayu; Qu, Jiamin; Shi, Jianbing; Tong, Bin; Cai, Zhengxu; Dong, Yuping published an article in 2022. The article was titled 《Amphiphilic and Zwitterionic Multi Arylpyrroles with Near-Infrared Aggregation-Induced Emission for Cell Membrane Imaging》, and you may find the article in ChemNanoMat.Electric Literature of C6H12O3 The information in the text is summarized as follows:

The cell membrane protects the cell stability and balance and participates in various physiol. activities as an exchange channel. Therefore, the real-time monitoring of cell membrane biol. dynamics can help us understand the physiol. state of the current cell. Herein, a type of amphiphilic near IR (NIR) aggregation-induced emission (AIE) mols. was designed and synthesized. Multiarylpyrroles (MAPs) with a dodecyl chain at the 1-position of the pyrrole ring, charged pyridinium sulfonate at the 2,5-position of the pyrrole ring and free rotating aryls at the 3-position of the pyrrole ring can target cell membranes. One of the MAPs, MAP22, had a maximum emission wavelength in the aggregation state of up to 721 nm with a large Stokes shift (∼280 nm). In addition, MAP22 nanoparticles can produce reactive oxygen species (ROS) with a quantum yield of 224%. Therefore, these AIE MAPs are promising candidates for theranostic nanoagents, including NIR fluorescence imaging to target cell membranes and ablate cancer cells by producing ROS. After reading the article, we found that the author used 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Electric Literature of C6H12O3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Electric Literature of C6H12O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Xin, Xing; Bissett, Amy; Wang, Joyce; Gan, Andrew; Dell, Kiri; Baroutian, Saeid published an article in 2021. The article was titled 《Production of liquid smoke using fluidised-bed fast pyrolysis and its application to green lipped mussel meat》, and you may find the article in Food Control.Reference of 2,5-Dimethoxytetrahydrofuran The information in the text is summarized as follows:

Liquid smoke flavouring as an all-natural food additive is usually prepared by smoldering or a carbonisation method. In this study, liquid smoke was prepared by fast pyrolysis technol. using a fluidised bed reactor with a yield of 30 wt%. GC-MS anal. showed that main functional compounds were furans, carbonyls and phenols. The fast pyrolysis liquid smoke presented a high antioxidant capacity with a total phenolic content of 21.9 mg GAE/mL. Cytotoxicity anal. indicated that it was as safe as com. liquid smoke products. This fast pyrolysis liquid smoke was diluted and applied to treat green lipped mussel meat, and the preserving effects were studied over 30-day refrigerated storage. The microbiol. anal. results showed bacteria growth was inhibited during the first 14 days of the storage period. The image and texture anal. results showed insignificant changes to liquid smoked mussel meat during storage except for color darkening and decreased hardness in meat texture. After reading the article, we found that the author used 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Reference of 2,5-Dimethoxytetrahydrofuran)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Reference of 2,5-Dimethoxytetrahydrofuran

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Synthetic Route of C6H12O3In 2020 ,《1-phenyl-8-[[4-(pyrrolo[1,2-a]quinoxalin-4-yl)phenyl]methyl]-1,3,8-triazaspiro[4.5]decan-4-one: synthesis, crystal structure and anti-leukemic activity》 appeared in Molbank. The author of the article were Guillon, Jean; Savrimoutou, Solene; Rubio, Sandra; Moreau, Stephane; Pinaud, Noel; Marchivie, Mathieu; Desplat, Vanessa. The article conveys some information:

A multi-step synthesis of 1-phenyl-8-[[4-(pyrrolo[1,2-a]quinoxalin-4-yl)phenyl]methyl]-1,3,8-triazaspiro[4.5]decan4-one using 2-nitroaniline as starting material was reported. Structure characterization of this original pyrrolo[1,2-a]quinoxaline derivative was achieved by FT-IR, 1H-NMR, 13C-NMR, X-Ray and HRMS spectral anal. This title compound showed interesting cytotoxic potential against several human leukemia cell lines (K562, HL60, and U937 cells). The experimental process involved the reaction of 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Synthetic Route of C6H12O3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Synthetic Route of C6H12O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

In 2022,Guillon, Jean; Savrimoutou, Solene; Albenque-Rubio, Sandra; Pinaud, Noel; Moreau, Stephane; Desplat, Vanessa published an article in Molbank. The title of the article was 《Synthesis, Crystal Structure and Anti-Leukemic Activity of 1,3-Dihydro-1-{1-[4-(4-phenylpyrrolo[1,2-a]quinoxalin-3-yl)benzyl]piperidin-4-yl}-2H-benzimidazol-2-one》.Application of 696-59-3 The author mentioned the following in the article:

Substituted pyrrolo[1,2-a]quinoxaline compound I was synthesized through a multi-step pathway starting from com. available 2-nitroaniline. A structure characterization of compound I was achieved by using FT-IR, 1H-NMR, 13C-NMR, X-Ray and HRMS spectral anal. This new compound I showed an interesting cytotoxic potential against several human leukemia cell lines (HL60, K562 and U937 cells).2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Application of 696-59-3) was used in this study.

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Application of 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Li, Shichen; Lv, Xueyan; Ren, Jianing; Feng, Lei; Ma, Chen published an article in 2022. The article was titled 《A Direct Method for Synthesis of Fluorinated Quinazolinones and Quinoxalines Using Fluorinated Acids without Metals or Additives》, and you may find the article in Synthesis.HPLC of Formula: 696-59-3 The information in the text is summarized as follows:

A direct method using trifluoroacetic acid as a CF3 source for the synthesis of 2-(trifluoromethyl)quinazolin-4-ones and 4-(trifluoromethyl)pyrrolo/indolo[1,2- a]quinoxalines without any catalysts or additives was reported; a wide range of fluorinated compounds were obtained in 52%-94% yield. The results came from multiple reactions, including the reaction of 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3HPLC of Formula: 696-59-3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.HPLC of Formula: 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Guan, Wen; Zhang, Yunlei; Yan, Changhao; Chen, Yao; Wei, Yanan; Cao, Yu; Wang, Fang; Huo, Pengwei published an article in 2022. The article was titled 《Base-Free Aerobic Oxidation of Furfuralcohols and Furfurals to Furancarboxylic Acids over Nitrogen-Doped Carbon-Supported AuPd Bowl-Like Catalyst》, and you may find the article in ChemSusChem.Recommanded Product: 696-59-3 The information in the text is summarized as follows:

Upgrading furfuralcs. and furfurals to furancarboxylic acids is of great significance for high value-added downstream chems. synthesis and biomass conversion. Developing an efficient catalyst is the key to acquiring a completely sustainable process. Herein, nitrogen-doped carbon-supported bimetallic AuPd bowl-like catalysts were synthesized. The surface wettability of nitrogen-doped carbon was well adjusted by the nitrification process. Benefiting from the alloying effect of bimetallic AuPd catalyst and the formation of hydroxyl radical initiated by H2O dissociation on the hydrophilic surface of nitrated nitrogen-doped carbon, base-free aerobic oxidation of 5-hydroxymethylfurfural (HMF) could produce the highest 2,5-furandicarboxylic acid (FDCA) yield of 93.9%. In-situ IR spectroscopy uncovered adsorption configuration of HMF, and the nitrated carbon surface was favorable for HMF and intermediates to enter the active sites, greatly promoting the catalytic oxidation process. Employing other furfuralcs. (furfuryl alc., furan-2,5-diyldimethanol, 2,5-bishydroxymethylfuran) as well as furfural and 5-methylfurfural as starting materials, 35.6-95.4% yield of furancarboxylic acids (FDCA, 2-furoic acid, 5-methyl-2-furoic acid) were also obtained. Moreover, the developed catalysts could maintain excellent stability and activity after four successive runs. This deep insight into the role of bimetallic synergy and surface wettability provides a basis for the rational design of the highly efficient catalysts for the oxidation of furfuralcs. and furfurals and related reactions. In the experimental materials used by the author, we found 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Recommanded Product: 696-59-3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Recommanded Product: 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

《Copper-Catalyzed Synthesis of Alkyl-Substituted Pyrrolo[1,2-a]quinoxalines from 2-(1H-Pyrrol-1-yl)anilines and Alkylboronic Acids》 was published in Synlett in 2020. These research results belong to Guan, Xin; Yan, Rulong. Recommanded Product: 2,5-Dimethoxytetrahydrofuran The article mentions the following:

A radical pathway for the construction of pyrrolo[1,2-a]quinoxalines I (R1 = H, 7-Me, 7-F, etc.; R2 = Me, Et, n-Pr, n-Bu, i-Pr; X = C, N) by using 2-(1H-pyrrol-1-yl)anilines and alkylboronic acids has been developed. Features of this process include Cu catalysis, readily accessible starting materials, and simple operations. Alkylboronic acids are used for the construction of pyrrolo[1,2-a]quinoxaline derivatives, and the desired products are obtained in moderate yields. In the experiment, the researchers used many compounds, for example, 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Recommanded Product: 2,5-Dimethoxytetrahydrofuran)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Recommanded Product: 2,5-Dimethoxytetrahydrofuran

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

SDS of cas: 696-59-3In 2020 ,《Pyrrolo[1,2-a]quinoxalines: Insulin Mimetics that Exhibit Potent and Selective Inhibition against Protein Tyrosine Phosphatase 1B》 appeared in ChemMedChem. The author of the article were Garcia-Marin, Javier; Griera, Mercedes; Sanchez-Alonso, Patricia; Di Geronimo, Bruno; Mendicuti, Francisco; Rodriguez-Puyol, Manuel; Alajarin, Ramon; de Pascual-Teresa, Beatriz; Vaquero, Juan J.; Rodriguez-Puyol, Diego. The article conveys some information:

PTP1B dephosphorylates insulin receptor and substrates to modulate glucose metabolism This enzyme is a validated therapeutic target for type 2 diabetes, but no current drug candidates have completed clin. trials. Pyrrolo[1,2-a]quinoxalines substituted at positions C1-C4 and/or C7-C8 were found to be nontoxic to cells and good inhibitors in the low- to sub-micromolar range, with the 4-benzyl derivative being the most potent inhibitor (0.24 μm). Some analogs bearing chlorine atoms at C7 and/or C8 kept potency and showed good selectivity compared to TCPTP (selectivity index >40). The most potent inhibitors behaved as insulin mimetics by increasing glucose uptake. The 4-benzyl derivative inhibited insulin receptor substrate 1 and AKT phosphorylation. Mol. docking and mol. dynamics simulations supported a putative binding mode for these compounds to the allosteric α3/α6/α7 pocket, but inconsistent results in enzyme inhibition kinetics were obtained due to the high tendency of these inhibitors to form stable aggregates. Computational calculations supported the druggability of inhibitors. In the experiment, the researchers used many compounds, for example, 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3SDS of cas: 696-59-3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.SDS of cas: 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

《A synthetic protocol for (-)-ketorolac; development of asymmetric gold(I)-catalyzed cyclization of allyl alcohol with pyrrole ring core》 was written by Sasaki, Ikuo; Yamasaki, Naoto; Kasai, Yusuke; Imagawa, Hiroshi; Yamamoto, Hirofumi. Electric Literature of C6H12O3 And the article was included in Tetrahedron Letters in 2020. The article conveys some information:

An asym. synthesis of (-)- and (+)-ketorolac was achieved with 89% ee using a novel Friedel-Crafts (FC) type C-C bond forming cyclization of an allyl alc. containing a pyrrole ring core in the presence of a bimetallic gold(I) salt complex prepared from a 2:2:1 combination of AuCl·SMe2, AgOTf and chiral Quinaphos. In the experiment, the researchers used many compounds, for example, 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Electric Literature of C6H12O3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Electric Literature of C6H12O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem