Parthasarathy, Anutthaman et al. published their research in FEBS Journal in 2010 | CAS: 53558-93-3

(R)-5-Oxotetrahydrofuran-2-carboxylicacid (cas: 53558-93-3) belongs to tetrahydrofuran derivatives. Solid acid catalysis, and the advantages often associated with their use, have been proved equally efficient for the synthesis of tetrahydrofurans or furans. It is more basic than diethyl ether and forms stronger complexes with Li+, Mg2+, and boranes. It is a popular solvent for hydroboration reactions and for organometallic compounds such as organolithium and Grignard reagents.Synthetic Route of C5H6O4

On the thermodynamic equilibrium between (R)-2-hydroxyacyl-CoA and 2-enoyl-CoA was written by Parthasarathy, Anutthaman;Buckel, Wolfgang;Smith, David M.. And the article was included in FEBS Journal in 2010.Synthetic Route of C5H6O4 This article mentions the following:

A combined exptl. and computational approach has been applied to investigate the equilibrium between several α-hydroxyacyl-CoA compounds and their 2-enoyl-CoA derivatives In contrast to those of their β, γ and δ counterparts, the equilibrium for the α-compounds are relatively poorly characterized, but qual. they appear to be unusually sensitive to substituents. Using a variety of techniques, we have succeeded in measuring the equilibrium constants for the reactions beginning from 2-hydroxyglutaryl-CoA and lactyl-CoA. A complementary computational evaluation of the equilibrium constants shows quant. agreement with the measured values. By examining the computational results, we arrive at an explanation of the substituent sensitivity and provide a prediction for the, as yet unmeasured, equilibrium involving 2-hydroxyisocaproyl-CoA. In the experiment, the researchers used many compounds, for example, (R)-5-Oxotetrahydrofuran-2-carboxylicacid (cas: 53558-93-3Synthetic Route of C5H6O4).

(R)-5-Oxotetrahydrofuran-2-carboxylicacid (cas: 53558-93-3) belongs to tetrahydrofuran derivatives. Solid acid catalysis, and the advantages often associated with their use, have been proved equally efficient for the synthesis of tetrahydrofurans or furans. It is more basic than diethyl ether and forms stronger complexes with Li+, Mg2+, and boranes. It is a popular solvent for hydroboration reactions and for organometallic compounds such as organolithium and Grignard reagents.Synthetic Route of C5H6O4

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Osmotic distillation technique was used for the total dealcoholization of a red wine (Aglianico grape variety) up to 0.19 vol.%. The dealcoholization process was performed in subsequent cycles which gave rise wine samples at different alcoholic degrees. The effect of processing on the main chemical and physical properties of Aglianico wine was evaluated. Among wine samples, no significant differences (p < 0.05) of oenological parameters such as pH, total acidity were found. Similarly, the total phenolic, flavonoids and tartaric esters content and the composition of organic acids did not show significant differences (p < 0.05) during the process. On the contrary, colour intensity and tonality of wine samples changed significantly when the alcohol reduction was over the 6.5 vol.%. Finally, the total dealcoholized wine showed properties similar to Aglianico wine except for the volatile compounds, which decreased over 98%. Hence, flavour enrichment may be required to produce a pleasurable and delicious non alcoholic beverage from wine. Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 53558-93-3 Reference:
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Rapid removal of recalcitrant organic contaminants from coking wastewater remains a challenge. Powder coke is a burden to coke plant and environment, has the potential as a cost-effective absorbent material. But its absorption capacity is limited by the dense crystalline carbon structure and low surface activity. This study proposes a facile method to fabricate powder coke-derived adsorbent by tuning the surface functional groups. Results revealed that the obtained powder coke-derived adsorbent presented a relatively smooth surface, worm-like pore structure and discernible graphitization degree. The O1S and N1S functional groups were increased from 27.7% to 52.2%. The adsorption of recalcitrant organic contaminants from coking wastewater was increased by 70%, implying significantly by the reduced UV254. The increased N and O-contained functional groups on the surface could introduce hydrophobic force and pi-pi EDA interactions, which are responsible to the enhanced interactions between powder coke-derived adsorbent and recalcitrant organic contaminants (PAHs and BAD, etc). The engineering aspect of the powder coke-derived adsorbent was discussed in the perspective of recent advances and challenges. This study provides scientific basis for its effective use of powder coke as an adsorbent for tertiary treatment of coke wastewater, so as to achieve the dual purposes of clean production and environmental protection.

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Tetrahydrofuran – Wikipedia,
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Traditional organic synthesis relies heavily on organic solvents for a multitude of tasks, including dissolving the components and facilitating chemical reactions, because many reagents and reactive species are incompatible or immiscible with water. Given that they are used in vast quantities as compared to reactants, solvents have been the focus of environmental concerns. Along with reducing the environmental impact of organic synthesis, the use of water as a reaction medium also benefits chemical processes by simplifying operations, allowing mild reaction conditions, and sometimes delivering unforeseen reactivities and selectivities. After the “watershed” in organic synthesis revealed the importance of water, the development of water-compatible catalysts has flourished, triggering a quantum leap in water-centered organic synthesis. Given that organic compounds are typically practically insoluble in water, simple extractive workup can readily separate a water-soluble homogeneous catalyst as an aqueous solution from a product that is soluble in organic solvents. In contrast, the use of heterogeneous catalysts facilitates catalyst recycling by allowing simple centrifugation and filtration methods to be used. This Review addresses advances over the past decade in catalytic reactions using water as a reaction medium.

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Four varietal wines Feteasc? Neagr?, Merlot, Cabernet Sauvignon and Pinot Noir from Romania were submitted to a liquid-liquid extraction with dichloromethane and analysed by gas chromatography-mass spectrometry (GC?MS). A total of 29 volatile compounds were identified and quantified over two periods of ageing. Wines were differentiated by a number of compounds, such as esters, higher alcohols, and lactones. During wine ageing, all chemicals changed in the volatile composition. Most of alcohols and acids (hexanoic and octanoic acids) increased during ageing, while the esters, except ethyl lactate and diethyl succinate, were found in lower concentrations as ageing time increased. Considering all the volatile compounds detected, esters and higher alcohols are the main contributors for Romanian red wines.

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Tetrahydrofuran – Wikipedia,
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Introduction Dog’s mercury (Mercurialis perennis L.) is a traditional European medicinal plant considered as a rich source of bioactive natural products. Yet phytochemical data of the plant are scant. Objective This study aimed to identify the hydrophilic phenolic constituents from M. perennis by aqueous and hydroalcoholic extraction. Methodology Extracts of herbal parts were investigated in-depth by HPLC(DAD)-MS/MS and GC/MS analyses. In addition, a novel compound was isolated and fully characterised by 1- and 2D-NMR experiments. Results Several conjugates of caffeic, p-coumaric and ferulic acids together with glucaric or 2-hydroxyglutaric acids (depsides) were detected in the aqueous extracts from aerial plant parts by use of LC-MS/MS techniques as well UV-spectral data. By implementation of preparative chromatography on polyamide pretreated with formic acid followed by vacuum liquid chromatography on reversed-phase C18-silica, one of the predominant depsides was isolated as a pure compound. The NMR spectra (1H and 13C NMR) together with 2D-hetereonuclear multiple bond correlation NMR experiments (gHMBC and gHSQC) and chiral GC investigation, allowed identification of this compound as (-)-(E)-caffeoyl-2-(R)-oxoglutarate. This structure was additionally supported by GC/MS data after silylation and methylation reactions. The hydroalcoholic extract from aerial parts was separated by solvent partition between ethyl acetate and n-butanol. The latter fraction (n-butanol) yielded a mixture of mono- and oligo-glycosides of kaempferol and quercetin, all of them being assigned by LC-MS/MS. Conclusions The present investigation constitutes the first comprehensive report on the hydrophilic constituents of the rarely studied plant Mercurialis and thus completes the phytochemical knowledge on M. perennis.

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Tetrahydrofuran – Wikipedia,
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The synthesis is described of a porphyrin alcohol (22) which has a structure very similar to that of porphyrin a (2).The model porphyrin was resolved by separation of its camphanate esters.Ozonolysis of the 2-nitrobenzoate of each enantiomer in tritiated form gave a derivative of 2-hydroxypentadioic acid whose configuration was determined by dilution analysis.It is demonstrated that correlation of the stereochemistry of porphyrin a with that of the model (22) will be possible by means of the (1)H and (19)F n.m.r. spectra of the corresponding esters with (-)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid.

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Increasing the output of essential oil (EO) has always been a concern during production, and this challenge has gained more attention from the essential oil industry. The salt process in which petals are immersed in sodium chloride solution in the process of hydrodistillation can effectively enhance the yield of EO, but it is unknown whether the quality of the EO changes after such treatment. Therefore, this study was designed to compare the properties of fresh rose essential oil (FREO) and salt rose essential oil (SREO), including compositions and their contents, characteristic aroma compounds and aroma profiles, as well as antioxidant activities. In the first part of the investigation, the compounds in FREO and SREO were identified by gas chromatography-mass spectrometry (GC/MS) and two-dimensional gas chromatography and time-of-flight mass spectrometry (GC × GC-TOF/MS). The aroma research was evaluated using the odor activity values (OAV), and the antioxidant properties were investigated for the total antioxidant capacity and the ability to scavenge DPPH free radicals. The results identified the 191 and 190 components in FREO and SREO using one-dimensional (1D) GC and two-dimensional (2D) GC, respectively; both were characterized by a high alcohol content, represented particularly by citronellol, geraniol and farnesol. Although some common compounds existed in the two EOs, the same compounds were found in different contents. For example, the citronellol content increased by 31.90 % from 256,491.61 mg/kg to 338,314.45 mg/kg after salt treatment, while the geraniol content decreased by 16.34 % from 47,909.22 mg/kg to 40,080.63 mg/kg. The analysis of aroma showed that salt treatment did not have a strong influence on the aroma types of the EOs as seen from the similar aroma profiles between FERO and SERO, and the performance of antioxidant activities of SREO was superior to that of FREO.

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Tetrahydrofuran – Wikipedia,
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In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 53558-93-3, name is (R)-(-)-5-Oxotetrahydrofuran-2-carboxylicacid, introducing its new discovery. SDS of cas: 53558-93-3

The compounds having a 4,11-dioxo-3-oxa-8(or 7)-thia-1-azatricyclo[7,2,0,02,6 ]undecane-2-carboxylic acid skeleton as the base structure, their esters and their salts are useful antibacterial agents.

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Tetrahydrofuran – Wikipedia,
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A bio-based nickel alginate film and copper alginate film were prepared via a facile ion exchange and casting approach. Their flame retardancy, thermal degradation and pyrolysis behavior, and thermal degradation mechanism were investigated systematically by the limiting oxygen index (LOI), vertical burning (UL-94), microscale combustion calorimetry (MCC), thermogravimetric analysis (TGA), thermogravimetric analyzer coupled with Fourier transform infrared analysis (TG-FTIR) and pyrolysis-gas chromatography-mass spectrometry (Py-GC-MS). It was shown that the nickel alginate film had a much higher LOI value (50.0%) than those of the sodium alginate film (24.5%) and copper alginate film (23.0%). Moreover, the nickel alginate film passed the UL-94 V-0 rating, while the sodium alginate film and copper alginate film showed no classification. Importantly, the peak of heat release rate (PHRR) of the nickel alginate film in the MCC test was much lower than those of the copper alginate film and sodium alginate film. This indicated that the introduction of nickel ions decreased the release of combustible gases. TGA results showed that the addition of copper ions and nickel ions accelerated the thermal degradation of alginates and changed the thermal degradation mechanism of the alginates. TG-FTIR and Py-GC-MS results indicated that the pyrolysis of copper alginate and nickel alginate produced much less flammable products than that of sodium alginate in the whole thermal degradation process. Finally, a possible degradation mechanism for copper alginate and nickel alginate was proposed. The results of our study provide useful information for understanding the flame retardancy mechanism of alginate as well as for designing bio-based materials with excellent fire retardancy.

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem