7175-81-7, An article , which mentions 7175-81-7, molecular formula is C5H11NO. The compound – (S)-(Tetrahydrofuran-2-yl)methanamine played an important role in people’s production and life.
Discovery of a novel series of CXCR3 antagonists
The discovery of a novel series of CXCR3 antagonists is described. Starting from an HTS positive, iterative optimization gave potent compounds (IC 50 15 nM in a chemotaxis assay). The strategy employed to improve the metabolic stability of these derivatives is described.
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Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem