Jensen, Pernille Rose published the artcileProbing the Lewis Acid Catalyzed Acyclic Pathway of Carbohydrate Conversion in Methanol by In Situ NMR, Application of 3-Hydroxydihydrofuran-2(3H)-one, the publication is ChemCatChem (2019), 11(20), 5077-5084, database is CAplus.
Future bioindustries will rely on the formation of diverse chems. at high yield through various reaction pathways. These pathways include reactions to a series of alpha-hydroxy esters and acids that can be formed from the conversion of C3-C6 carbohydrates by Lewis acidic catalysts in alcs. and water. Definitive kinetic and mechanistic insights to support the development of carbohydrate conversion processes are arguably less developed than for analogous biocatalytic processes. Here, we visualize acyclic pathways of carbohydrate dehydration, using the acyclic C4 carbohydrate erythrulose as a probe mol. for the conversion by homogeneous SnCl4 in methanol. In situ studies allow the detection of previously postulated intermediates, identify the branch point to competing products and provide energetic and mechanistic insight by kinetic anal. Reversibility of reactions, stereoselectivity and differential propensity for deuterium incorporation in competing pathways can be tracked by the formation of compounds with asym. mass distribution.
ChemCatChem published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Application of 3-Hydroxydihydrofuran-2(3H)-one.
Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem