Yamaguchi, Sho published the artcileMechanistic Studies on the Cascade Conversion of 1,3-Dihydroxyacetone and Formaldehyde into α-Hydroxy-γ-butyrolactone, Product Details of C4H6O3, the publication is ChemSusChem (2015), 8(5), 853-860, database is CAplus and MEDLINE.
The chem. synthesis of com. and industrially important products from biomass-derived sugars is absolutely vital to establish biomass utilization as a sustainable alternative source of chem. starting materials. α-Hydroxy-γ-butyrolactone is a useful synthetic intermediate in pharmaceutical chem., and so novel biomass-related routes for its production may help to validate this eco-friendly methodol. Herein, we report the specific catalytic activity of homogeneous tin halides to convert the biomass-derived triose sugar 1,3-dihydroxyacetone and formaldehyde into α-hydroxy-γ-butyrolactone. A detailed screening of catalysts showed the suitability of tin catalysts for this reaction system, and isotope experiments using [D2]paraformaldehyde, substrate screening, and time profile measurements allowed us to propose a detailed reaction pathway. In addition, to elucidate the activated species in this cascade reaction, the effect of addnl. water and the influence of addnl. Bronsted acids on the reaction preferences for the formation of α-hydroxy-γ-butyrolactone, lactic acid, and vinyl glycolate were investigated. The active form of the Sn catalyst was investigated by 119Sn NMR spectroscopy.
ChemSusChem published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C12H10FeO4, Product Details of C4H6O3.
Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem