Nucleosides of 2-azapurines. 7H-Imidazo[4,5-d]-1,2,3-triazines. 2 was written by Montgomery, John A.; Laseter, Anne G.; Shortnacy, Anita T.; Clayton, Sarah J.; Thomas, H. Jeanette. And the article was included in Journal of Medicinal Chemistry in 1975.Name: 9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol The following contents are mentioned in the article:
A series of 7 title compounds, prepared by enzymic deamination of 2-azaadenine nucleosides or ring cleavage of hypoxanthine nucleosides followed by nitrosative ring closure to the 2-azahypoxanthine nucleosides, were tested in cultures of human epidermoid carcinoma Number 2 cells and sublines. 2-Azaadenosine (I) [146-94-1] was active against all cell lines except those lacking both adenosine kinase and hypoxanthine-guanine phosphoribosyltransferase. The 2-azaadenine nucleosides could be metabolized to the cytotoxic nucleotides by 2 pathways, but the 2-azahypoxanthine nucleosides activity resulted from cleavage to 2-azahypoxanthine. This study involved multiple reactions and reactants, such as 9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol (cas: 13146-72-0Name: 9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol).
9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol (cas: 13146-72-0) belongs to tetrahydrofuran derivatives.Tetrahydrofuran has many industry uses as a solvent including in natural and synthetic resins, high polymers, fat oils, rubber, polymer. Tetrahydrofuran (THF) is primarily used as a precursor to polymers including for surface coating, adhesives, and printing inks.Name: 9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol
13146-72-0;9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol;The future of 13146-72-0;New trend of C10H12N4O4 ;function of 13146-72-0