Hypoxanthine nucleoside counterparts of the antibiotic, cordycepin was written by Nair, Vasu; Lyons, Arthur G.. And the article was included in Tetrahedron in 1990.Related Products of 13146-72-0 The following contents are mentioned in the article:
Analogs I (R = iodo, CH2CH:CH2, CH:CH2, CHO, CH2COMe, CN) of 3′-deoxyinosine, although of potential RNA antiviral interest, are virtually unknown. This paper reports on approaches to the synthesis of base-modified hypoxanthine 3′-deoxynucleosides. All of the target compounds are new and contain functionality at the 2-position that can be further elaborated for the synthesis of a variety of other novel analogs of 3′-deoxyinosine. Intact natural guanosine was used as the precursor and the key transformations utilized were regioselective bissilylation, thermal radical deoxygenation, regiospecific radical halogenation, metal-mediated functionalization, and selective ozonolysis. The synthetic approaches described have considerable generality in terms of entry to novel analogs of 3′-deoxyinosine. This study involved multiple reactions and reactants, such as 9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol (cas: 13146-72-0Related Products of 13146-72-0).
9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol (cas: 13146-72-0) belongs to tetrahydrofuran derivatives. THF (Tetrahydrofuran) is water-miscible and has a low viscosity making it a highly versatile solvent used in a variety of industries. Oxidations have also proved to be valuable and efficient approaches to chiral tetrahydrofuran derivatives.Related Products of 13146-72-0
13146-72-0;9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol;The future of 13146-72-0;New trend of C10H12N4O4 ;function of 13146-72-0