Synthesis of new nebularine analogues and their inhibitory activity against adenosine deaminase was written by Lougiakis, Nikolaos; Marakos, Panagiotis; Pouli, Nicole; Fragopoulou, Elisabeth; Tenta, Roxane. And the article was included in Chemical & Pharmaceutical Bulletin on February 28,2015.HPLC of Formula: 550-33-4 The following contents are mentioned in the article:
A number of new 2,6-disubstituted-1-deazanebularine analogs as well as two structurally related pyrazole-fused tricyclic nucleosides were prepared Their synthesis was carried out by the conversion of 6-amino-2-picoline to a suitable 1-deazapurine, followed by a Vorbruggen type glycosylation and subsequent elaboration of the condensed pyrazole ring. The synthesized nebularine analogs proved to be weak adenosine deaminase inhibitors. This study involved multiple reactions and reactants, such as (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(9H-purin-9-yl)tetrahydrofuran-3,4-diol (cas: 550-33-4HPLC of Formula: 550-33-4).
(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(9H-purin-9-yl)tetrahydrofuran-3,4-diol (cas: 550-33-4) belongs to tetrahydrofuran derivatives. THF (Tetrahydrofuran) is water-miscible and has a low viscosity making it a highly versatile solvent used in a variety of industries. Tetrahydrofuran reaction with hydrogen sulfide: In the presence of a solid acid catalyst, tetrahydrofuran reacts with hydrogen sulfide to give tetrahydrothiophene.HPLC of Formula: 550-33-4
550-33-4;(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(9H-purin-9-yl)tetrahydrofuran-3,4-diol;The future of 550-33-4;New trend of C10H12N4O4 ;function of 550-33-4