5061-21-2, 2-Bromo-4-butanolide is a Tetrahydrofurans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,5061-21-2
General procedure: To a vigorously stirring solution of a-imino ester 1 (0.5 mmol, 1 equiv) and alpha-halo ester (2c-k, 1.5 mmol, 3 equiv) in THF/DMF (1 mL) was added indium powder (1 mmol, 2 equiv). The mixture was allowed to stir vigorously at 30 C for given time. After this period, the reaction mixture was quenched with 2 mL of water and transferred to a separating funnel and extracted using ethyl acetate (315 mL). The combined organic layers were dried over anhydrous Na2SO4. Then the solvent was evaporated under vacuum. Purification of the resulting crude reaction mixture by column chromatography on silica gel (EtOAc/Hexane as eluent) gave the product 10 (see Tables 4 and 5 and Scheme 4 for individual entries).
5061-21-2 2-Bromo-4-butanolide 95463, aTetrahydrofurans compound, is more and more widely used in various fields.
Reference£º
Article; Aslam, Nayyar Ahmad; Babu, Srinivasarao Arulananda; Sudha, Arya Jayadev; Yasuda, Makoto; Baba, Akio; Tetrahedron; vol. 69; 32; (2013); p. 6598 – 6611;,
Tetrahydrofuran – Wikipedia
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