Graves, Brian M.; Johnson, Tyler J.; Nishida, Robert T.; Dias, Ryan P.; Savareear, Benjamin; Harynuk, James J.; Kazemimanesh, Mohsen; Olfert, Jason S.; Boies, Adam M. published their research in Scientific Reports on December 31 ,2020. The article was titled 《Comprehensive characterization of mainstream marijuana and tobacco smoke》.Reference of 3-Hydroxydihydrofuran-2(3H)-one The article contains the following contents:
Recent increases in marijuana use and legalization without adequate knowledge of the risks necessitate the characterization of the billions of nanoparticles contained in each puff of smoke. Tobacco smoke offers a benchmark given that it has been extensively studied. Tobacco and marijuana smoke particles are quant. similar in volatility, shape, d. and number concentration, albeit with differences in size, total mass and chem. composition Particles from marijuana smoke are on average 29% larger in mobility diameter than particles from tobacco smoke and contain 3.4 times more total mass. New measurements of semivolatile fractions determined that >97% of the mass and volume of the particles from either smoke source are comprised of semivolatile compounds For tobacco smoke and marijuana smoke, resp., 4350 and 2575 different compounds are detected, of which 670 and 536 (231 in common) are tentatively identified, and of these, 173 and 110 different compounds (69 in common) are known to cause neg. health effects through carcinogenic, mutagenic, teratogenic, or other toxic mechanisms. This study demonstrates striking similarities between marijuana and tobacco smoke in terms of their phys. and chem. properties. In the experiment, the researchers used many compounds, for example, 3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9Reference of 3-Hydroxydihydrofuran-2(3H)-one)
3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9) is a 5-membered cyclic ester. It was obtained via tin-conversion of biomass-derived 1,3-dihydroxyacetone (DHA) and formaldehyde. And it may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis.Reference of 3-Hydroxydihydrofuran-2(3H)-one
Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem