COA of Formula: C9H10O3In 1996, McCluskey, Adam;Taylor, Cherie;Quinn, Ronald J.;Suganuma, Masami;Fujiki, Hirota published 《Inhibition of protein phosphatase 2A by cantharidin analogs》. 《Bioorganic & Medicinal Chemistry Letters》published the findings. The article contains the following contents:
The syntheses of several cantharidin analogs and their biochem. effects on protein phosphatase 2A are described. Comparison of the PP2A inhibition of these cantharidin analogs has shown that the 7-oxo moiety and the anhydride system contribute to the biochem. activity. The diacid forms of several anhydrides showed reduced inhibition of PP2A. To complete the study, the researchers used (3aR,4S,7R,7aS)-rel-Hexahydro-4,7-methanoisobenzofuran-1,3-dione (cas: 14166-28-0) .
In the laboratory, (3aR,4S,7R,7aS)-rel-Hexahydro-4,7-methanoisobenzofuran-1,3-dione(14166-28-0) is a popular solvent when its water miscibility is not an issue. It is more basic than diethyl ether and forms stronger complexes with Li+, Mg2+, and boranes.COA of Formula: C9H10O3 It is a popular solvent for hydroboration reactions and for organometallic compounds such as organolithium and Grignard reagents.
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem