Reference of 1-Hexyl-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 1-Hexyl-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione, is researched, Molecular C13H20N4O2, CAS is 1028-33-7, about Dual use of a chemical auxiliary: molecularly imprinted polymers for the selective recovery of products from biocatalytic reaction mixtures. Author is Larsen, Aaron T.; Lai, Tiffany; Polic, Vanja; Auclair, Karine.
Auxiliary-directed biocatalysis is a powerful and relatively benign tool for chem. synthesis. We recently reported the use of theobromine as a chem. auxiliary for directing CYP3A4-catalyzed oxidations with predictable regio-, chemo- and stereo-selectivity (J.Am. Chem. Soc., 2011, 133, 7853). This highly successful strategy enabled the direct, regio- and stereo-selective hydroxylation of unactivated C-H bonds. However, recovering the products and starting materials from the resulting biocatalytic mixtures has proven challenging. To address this issue, we capitalized on the chem. auxiliary present on the starting material and enzymic reaction products. The chem. auxiliary was used as a template to generate molecularly imprinted polymers (MIPs). When used in solid-phase extractions, the MIPs reported here allow for the recovery (>90%) of theobromine-containing products and starting materials from complex mixtures such as cellular membrane extracts This strategy, which avoids the use of large amounts of organic solvents, represents an effective, easily-tailored, and reusable way to improve the recovered yield of biocatalytic transformations while extending the usefulness of a chem. auxiliary.
This literature about this compound(1028-33-7)Reference of 1-Hexyl-3,7-dimethyl-1H-purine-2,6(3H,7H)-dionehas given us a lot of inspiration, and I hope that the research on this compound(1-Hexyl-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem