Introduction of a new synthetic route about 20028-53-9

This literature about this compound(20028-53-9)Synthetic Route of C7H6ClNOhas given us a lot of inspiration, and I hope that the research on this compound(2-Amino-5-chlorobenzaldehyde) can be further advanced. Maybe we can get more compounds in a similar way.

Synthetic Route of C7H6ClNO. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 2-Amino-5-chlorobenzaldehyde, is researched, Molecular C7H6ClNO, CAS is 20028-53-9, about Friedlander synthesis and structure characterization of novel quinoline derivatives.

A series of 2-fluoro-6H-chromeno[4,3-b]quinoline derivatives I (R = H, 5-Cl, 3,5-Br2, 3,6-(MeO)2) were synthesized by the Friedlander condensation of substituted (unsubstituted) o-aminobenzaldehyde with 6-fluorochroman-4-one in alk. ethanol solutions In addition, the expected products can give 2-(3-(ethoxymethyl)quinolin-2-yl)-4-fluorophenol derivatives II (R = H, 5-Cl, 3,5-Br2, 3,6-(MeO)2) by nucleophilic substitution reaction in alk. solutions The structures of the title compounds I and II were characterized by elemental anal., IR, 1H NMR and MS techniques. The compound II(R = 3,6-(MeO)2) was confirmed by X-ray single crystal diffraction anal.

This literature about this compound(20028-53-9)Synthetic Route of C7H6ClNOhas given us a lot of inspiration, and I hope that the research on this compound(2-Amino-5-chlorobenzaldehyde) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem