The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Physical changes and mutagenesis》. Authors are Setlow, R. B..The article about the compound:8-Bromoguaninecas:3066-84-0,SMILESS:NC(N1)=NC(NC(Br)=N2)=C2C1=O).Recommanded Product: 8-Bromoguanine. Through the article, more information about this compound (cas:3066-84-0) is conveyed.
Uv (280 mμ) irradiation of DNA in vitro and in vivo results in dimerization of adjacent thymines in the same polynucleotide chain. These dimers are split by short wave uv (240 mμ) and by enzymic action plus visible light. In either case the decrease in the number of dimers is correlated with the increase in the biol. activity of DNA or increase in colony-forming ability of irradiated cells. In an in vitro polymerase system there was slow polymerization around thymine dimers, the product was deficient in adenine, and the base composition was not complementary to the irradiated primer. In Escherichia coli the dimers were removed from the DNA in the form of small oligonucleotides.
In addition to the literature in the link below, there is a lot of literature about this compound(8-Bromoguanine)Recommanded Product: 8-Bromoguanine, illustrating the importance and wide applicability of this compound(3066-84-0).
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem