Fernandez-Maestre, Roberto; Doerr, Markus published an article about the compound: (S)-Butan-2-ol( cas:4221-99-2,SMILESS:C[C@H](O)CC ).SDS of cas: 4221-99-2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:4221-99-2) through the article.
Racemic mixtures of twelve common α-amino acids and three chiral drugs were tested for the separation of their enantiomers by ion mobility spectrometry (IMS)-quadrupole mass spectrometry (MS). Separations were tested by introducing chiral selectors in the mobility spectrometer buffer gas. (R)-α-(trifluoromethyl) benzyl alc., (R)-tetrahydrofuran-2-carbonitrile, (L)-Et lactate, Me (S)-2-chloropropionate, and the R and S enantiomers of 2-butanol and 1-Ph ethanol were evaluated as chiral selectors. Exptl. conditions were varied during the tests including buffer gas temperature, concentration, and type of chiral selectors, analyte concentration, electrospray voltage, electrospray (ESI) solvent pH, and buffer gas flow. The individual enantiomers yielded different drift times for periods of up to 8 h in a few experiments; such drift times were sufficiently different (~0.3 ms) to partially resolve the enantiomers in racemic mixtures, but these mixtures always yielded a single mobility peak at the exptl. conditions tested with a drift time similar to that of one of the enantiomers. Energy calculations of the chiral selector-ion interactions showed that these separations are unlikely using 2-butanol as chiral selector but they might be feasible depending on the nature of chiral selectors and the type of enantiomers.
From this literature《On the separation of enantiomers by drift tube ion mobility spectrometry》,we know some information about this compound(4221-99-2)SDS of cas: 4221-99-2, but this is not all information, there are many literatures related to this compound(4221-99-2).
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem