Some examples of the diverse research done by chemistry experts include discovery of new medicines and vaccines, improving understanding of environmental issues, and development of new chemical products and materials. SDS of cas: 453-20-3
The invention provides a pharmaceutical intermediate (S)- 3 – hydroxy tetrahydrofuran preparation method. The method other than racemic 1, 2, 4 – butanetriol as raw materials synthesis of racemic 3 – hydroxy tetrahydrofuran, then esterification of racemic tetrahydrofuran-yl – 3 – fatty acid ester. By lipase hydrolysis in the racemic mixture of (R)- tetrahydrofuran-based – 3 – fatty acid ester after, in in the hydrolysis product under the condition of separating, using the mitsunobu reaction will be hydrolyzed to obtain the of (R)- 3 – hydroxy tetrahydrofuran is converted into (S)- tetrahydrofuran-based – 3 – carboxylic acid ester, finally under alkaline condition all of the tetrahydrofuran ester hydrolyzed to obtain the final product (S)- 3 – hydroxy tetrahydrofuran. (by machine translation)
A catalyst does not appear in the overall stoichiometry of the reaction it catalyzes. In my other articles, you can also check out more blogs about 453-20-3. SDS of cas: 453-20-3
Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem