Synthetic Route of 4971-56-6, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.4971-56-6, Name is Furan-2,4(3H,5H)-dione, molecular formula is C4H4O3. In a Article,once mentioned of 4971-56-6
The one-step three-component microwave assisted synthesis between aromatic aldehydes with tetronic acid or indan-1,3-dione readily formed the Knoevenagel adducts that underwent addition of 3-methylisoxazol-5-amine 1 to form the isoxazolo[5,4-b]pyridine products 8[a,b,d,e,g] in 67?90% yield. The multicomponent reaction using dimedone formed the respective addition products 4-aryl-3,7,7-trimethyl-isoxazolo[5,4-b]quinolin-5(6H)-ones 8[c,f,h] (36?79%). In contrast, the sonication of an aryl aldehyde and dimedone with an equivalent amount of 2-hydroxyammonium formate exclusively generated the Knoevenagel adduct 4c via hydro-4c. When microwaved either with 3-amino-5-methylisoxazole 1 or 3,4,5-trimethoxyaniline 14 in ethanoic acid?ethylacetate (1:1), tetrahydroacridones 15[a,b] formed in high yields (88?92%). Importantly, this two-step reaction sequence generates highly reproducible and pure products.
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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem