Archives for Chemistry Experiments of 1679-47-6

If you are interested in 1679-47-6, you can contact me at any time and look forward to more communication. category: Tetrahydrofurans

Chemistry is traditionally divided into organic and inorganic chemistry. category: Tetrahydrofurans, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 1679-47-6

beta,beta,beta’,beta’-Tetrasubstituted, long-chain dioic acids of the general formula HOOC-C(XY)-C(R2)-Q-C(XY)-COOH have been synthesized and evaluated as hypotriglyceridemic-hypocholesterolemic agents in rats and as antidiabetogenic agents in ob/ob diabetic mice.The free carboxyl function of analogues of the series was mandatory for their hypolipidemic-antidiabetogenic effect while nonhydrolyzable diesters were inactive.Other structure-activity relationships were determined as a function of the overall chain length (C12-C22), alpha,alpha’-substitutions (X,Y=H,F,Cl,Br,OH,CN), beta,beta’-substitutions (R=CH3,C6H5), and core substitutions 2, 1,4-C6H4<(CH2)3>2, 1,4-C6H4(CH=CHCH2)2, CH2(OCH2CH2)3OCH2)>.The most effective hypolipidemic-antidiabetogenic members of the series were alpha,alpha’-nonsubstituted, beta,beta’-methyl-substituted analogues of 14-18-carbon chains having either a saturated aliphatic core or a 1,4-bis(propenyl)benzene core in the cis/trans configuration.The hypotriglyceridemic rather than the hypocholesterolemic capacity of members of the series was found to correlate with their respective capacities as liver peroxisomal proliferation in rats.

If you are interested in 1679-47-6, you can contact me at any time and look forward to more communication. category: Tetrahydrofurans

Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem