Related Products of 117752-88-2, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 117752-88-2, (R)-3-Amino-g-butyrolactone hydrochloride, introducing its new discovery.
Single Step Conversion of Chiral Carnitine and Derivatives into (S)- and (R)-beta-Substituted-gamma-Butyrolactones
This paper describes an efficient single step transformation of chiral carnitine and carnitine derivatives into stereoisomerically pure (S)- and (R)-beta-substituted-gamma-butyrolactones, obtained by intramolecular nucleophilic displacement. (S)- Or (R)-carnitine and (R)-aminocarnitine inner salts give beta-hydroxy-gamma-butyrolactone and beta-amino-gamma-butyrolactone respectively (82% and 77%) with the same configuration as the starting material. (R)-Acetylaminocarnitine inner salt gives (R)-beta-acetylamino-gamma-butyrolactone (90%), while (R)-acetylcarnitine gives 2(5H)-furanone under the same reaction conditions (77%, via cyclization and subsequent elimination reaction). (R)-N-Benzyloxycarnitineamide gives a mixture of pyrrolidinone (11%) and furanoyl imidate (50%) derivatives. The direct transformation of waste (S)-carnitine into the valuable (S)-beta-hydroxy-gamma-butyrolactone or (after acetylation) into the precious 2(5H)-furanone is of particular interest.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Related Products of 117752-88-2. In my other articles, you can also check out more blogs about 117752-88-2
Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem