Synthetic Route of 453-20-3, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.453-20-3, Name is 3-Hydroxytetrahydrofuran, molecular formula is C4H8O2. In a Patent£¬once mentioned of 453-20-3
Heterocyclic derivative of tyrosine kinase inhibitors (by machine translation)
The invention belongs to the field of medical technology, in particular to general formula (I) shown in the heterocyclic derivative of tyrosine kinase inhibitors, pharmaceutically acceptable salts thereof, esters thereof and their stereoisomers, wherein Y, W, Q, m, L, R 1, R 2, R 3, R 4, R 5, R 6, R 7, R 7 ‘, R 8, R 8’ as defined in the specification. The invention also relates to methods of preparing such compounds, pharmaceutical preparations comprising these compounds and pharmaceutical compositions, and the use of these compounds as tyrosine kinase inhibitors for the preparation of medicine for preventing and/or treatment of the mutant EGFR cancer diseases and EGFR T790M diseases caused by mutations in the drug-resistant application of the medicament. (by machine translation)
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 453-20-3
Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem