4100-80-5, Name is 3-Methyldihydrofuran-2,5-dione, belongs to Tetrahydrofurans compound, is a common compound. Recommanded Product: 4100-80-5In an article, once mentioned the new application about 4100-80-5.
Synthesis of simple analogues of methyllycaconitine – An efficient method for the preparation of the N-substituted anthranilate pharmacophore
The synthesis of several A and AE ring analogues of the alkaloid methyllycaconitine is reported. The key 2-(2?-methylsuccinimido)benzoate ester pharmacophore is introduced using an efficient two step procedure. Esterification of the alcohol precursors with N-(trifluoroacetyl)anthranilic acid under Steglich conditions followed by sodium borohydride mediated cleavage of the trifluoroacetyl group affords the anthranilate esters. Subsequent fusion with methylsuccinic anhydride affords the N-substituted anthranilate derivatives containing the key pharmacophore present in a range of commonly occurring Delphinium and Aconitum alkaloids.
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 4100-80-5
Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem