19311-37-6, 3-Bromotetrahydrofuran is a Tetrahydrofurans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of tert-butyl (6S)-3-hydroxy-6-methyl-6,7-dihydro-4H-pyrazolo[l,5- a]pyrazine-5-carboxylate (compound 3f, 70.0 mg, 0.277 mmol) and 3-bromotetrahedronfuran (62.7 mg, 0.415 mmol) in DMF (4.0 ml) was added NaH (16.6 mg, 0.415 mmol) at room temperature. The reaction mixture was stirred at room temperature for 3 h, then quenched with water (5.0 mL), diluted with EtOAc (60 mL). The organic layer was washed with water and brine, dried over Na2S04 and concentrated. The residue was purified by column chromatography (eluted with PE:EA = 10: 1-1: 1) to afford compound 3g (50.0 mg) as a yellow oil. LCMS (M+H+): 324., 19311-37-6
As the paragraph descriping shows that 19311-37-6 is playing an increasingly important role.
Reference£º
Patent; F. HOFFMANN-LA ROCHE AG; HOFFMANN-LA ROCHE INC.; HU, Taishan; LIU, Haixia; (78 pag.)WO2017/198744; (2017); A1;,
Tetrahydrofuran – Wikipedia
Tetrahydrofuran | (CH2)3CH2O – PubChem