One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, COA of Formula: C5H6O3, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 4100-80-5, Name is 3-Methyldihydrofuran-2,5-dione, molecular formula is C5H6O3
Synthesis and pharmacological evaluation of 6-arylpyridazinones as potent vasorelaxants
Preclinical Research As part of a research program to identify compounds with potent antihypertensive properties, a new series of dihydropyridazin-3(2H)- one analogs was synthesized and evaluated for vasodilator activity in rat thoracic aortic rings. Most of the newly synthesized compounds displayed good vasorelaxant activity as compared with SK&F-93741 and hydralazine, with the N2-unsubstituted 4-isobutyramidophenylpyridazinone derivative 5 being the most potent vasorelaxant, producing vasorelaxation greater than that of hydralazine and equipotent to SK&F-93741. A significant effect of the 6-phenyl substituents and substitution at N-2 position of pyridazinone nucleus on the vasodilatory activity was observed.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. COA of Formula: C5H6O3, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 4100-80-5, in my other articles.
Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem