Synthetic Route of 89364-31-8, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 89364-31-8, Tetrahydrofuran-3-carboxylic acid, introducing its new discovery.
Pyridine carboxamides: Potent palm site inhibitors of HCV NS5B polymerase
Pyridine carboxamide-based inhibitors of the hepatitis C virus (HCV) NS5B polymerase were diversified and optimized to a variety of topologically related scaffolds. In particular, the 2-methyl nicotinic acid scaffold was developed into inhibitors with improved biochemical (IC50-GT1b = 0.014 muM) and cell-based HCV replicon potency (EC50-GT1b = 0.7 muM). Biophysical and biochemical characterization identified this novel series of compounds as palm site binders to HCV polymerase.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Synthetic Route of 89364-31-8. In my other articles, you can also check out more blogs about 89364-31-8
Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem