Synthetic Route of 121138-01-0, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 121138-01-0, Name is 3-Iodotetrahydrofuran,introducing its new discovery.
Combination of NH2OH¡¤HCl and NaIO4: an effective reagent for molecular iodine-free regioselective 1,2-difunctionalization of olefins and easy access of terminal acetals
We have demonstrated a new application of our oxidizing reagent, a combination of NH2OH¡¤HCl and NaIO4, in the first generalized regioselective 1,2-difunctionalization of olefins. It is a general method for the preparation of beta-iodo-beta?-hydroxy ethers, beta-iodo ethers, beta-iodohydrin, and beta-iodo acetoxy compounds using different reaction media. The reactions are highly regioselective, always affording Markovnikov’s type addition products. The methodology is also applicable for the easy access of terminal acetals. Molecular iodine-free synthesis, room temperature reaction conditions, high yields, use of less expensive reagents, mild reaction conditions, broad applicability of nucleophiles, and applicability for gram-scale synthesis are the notable advantages of this present protocol.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 121138-01-0, and how the biochemistry of the body works.Synthetic Route of 121138-01-0
Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem