Related Products of 165253-29-2, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 165253-29-2, Name is 3-(Bromomethyl)tetrahydrofuran, molecular formula is C5H9BrO. In a Article£¬once mentioned of 165253-29-2
Discovery and Characterization of CD12681, a Potent RORgamma Inverse Agonist, Preclinical Candidate for the Topical Treatment of Psoriasis
With possible implications in multiple autoimmune diseases, the retinoic acid receptor-related orphan receptor RORgamma has become a sought-after target in the pharmaceutical industry. Herein are described the efforts to identify a potent RORgamma inverse agonist compatible with topical application for the treatment of skin diseases. These efforts culminated in the discovery of N-(2,4-dimethylphenyl)-N-isobutyl-2-oxo-1-[(tetrahydro-2H-pyran-4-yl)methyl]-2,3-dihydro-1H-benzo[d]imidazole-5-sulfonamide (CD12681), a potent inverse agonist with in vivo activity in an IL-23-induced mouse skin inflammation model.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Related Products of 165253-29-2. In my other articles, you can also check out more blogs about 165253-29-2
Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem