Krishna, Marothu Vamsi et al. published their research in Acta Ciencia Indica, Chemistry in 2006 | CAS: 81403-68-1

N-(3-((4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)propyl)tetrahydrofuran-2-carboxamide hydrochloride (cas: 81403-68-1) belongs to tetrahydrofuran derivatives. THF (Tetrahydrofuran) is water-miscible and has a low viscosity making it a highly versatile solvent used in a variety of industries. Tetrahydrofuran reaction with hydrogen sulfide: In the presence of a solid acid catalyst, tetrahydrofuran reacts with hydrogen sulfide to give tetrahydrothiophene.Quality Control of N-(3-((4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)propyl)tetrahydrofuran-2-carboxamide hydrochloride

Spectrophotometric determination of alfuzocin hydrochloride in pure form and in pharmaceutical formulations by using Folin-Ciocalteu reagent and potassium ferricyanide was written by Krishna, Marothu Vamsi;Sankar, Dannana Gowri. And the article was included in Acta Ciencia Indica, Chemistry in 2006.Quality Control of N-(3-((4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)propyl)tetrahydrofuran-2-carboxamide hydrochloride This article mentions the following:

Two accurate, simple and precise spectrophotometric methods (1 and 2) are described for the determination of alfuzocin-HCl (AFZ) in bulk and in pharmaceutical formulations. Method 1 was based on the reduction of Folin-Ciocalteu reagent by AFZ, in presence of sodium hydroxide. The colored species formed shows absorption maximum at 760 nm. Method 2 was based on the oxidation of AFZ by ferric chloride in the presence of potassium ferricyanide. The colored complex formed was measured at 750 nm. The optimum exptl. parameters for the color production are selected. Beer’s law is valid with in a concentration range of 50-250 μg mL-1 for method 1 and 8.0-40.0 μg mL-1 for method 2. The results obtained were reproducible and statistically validated and found to be suitable for the assay of alfuzocin. In the experiment, the researchers used many compounds, for example, N-(3-((4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)propyl)tetrahydrofuran-2-carboxamide hydrochloride (cas: 81403-68-1Quality Control of N-(3-((4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)propyl)tetrahydrofuran-2-carboxamide hydrochloride).

N-(3-((4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)propyl)tetrahydrofuran-2-carboxamide hydrochloride (cas: 81403-68-1) belongs to tetrahydrofuran derivatives. THF (Tetrahydrofuran) is water-miscible and has a low viscosity making it a highly versatile solvent used in a variety of industries. Tetrahydrofuran reaction with hydrogen sulfide: In the presence of a solid acid catalyst, tetrahydrofuran reacts with hydrogen sulfide to give tetrahydrothiophene.Quality Control of N-(3-((4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)propyl)tetrahydrofuran-2-carboxamide hydrochloride

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem