Immobilizing taste-bud tissues of pigs to prepare bitterness biosensor was written by Qiao, Lixin;Liu, Tingting;Pang, Guangchang. And the article was included in Shipin Kexue (Beijing, China) in 2015.Related Products of 126-14-7 This article mentions the following:
Using sodium alginate-starch gel as a fixing agent, taste-bud tissues of pigs were fixed between two nuclear microporous membranes to make a sandwich-type sensing membrane, which was then fixed to a glassy carbon electrode to make a biosensor electrode. By using electrochem. workstation, the current produced when sucrose octaacetate, denatonium and quercetin stimulated their corresponding receptors were tested. The results showed that the lowest limit of detection of this biosensor for sucrose octaacetate, denatonium and quercetin were 1 × 10-14, 1 × 10-13 and 1 × 10-14 mol/L and the maximum rate of change of the current was found at concentration levels of 1 × 10-8, 1 × 10-6 and 1 × 10-9 mol/L, resp., indicating that their receptors are saturated It was demonstrated that the interaction curves of sucrose octaacetate, denatonium and quercetin with their resp. receptors exhibited high correlation (R2 = 0.957 3, 0.987 3 and 0.996 4) in the concentration ranges of 1 × 10-14-1 × 10-11 mol/L, 1 × 10-13-1 × 10-7 mol/L and 1 × 10-14-1 × 10-9 mol/L, resp. This study not only quant. determined the interaction of the taste receptor and bitter substances with a new biosensor, but also provided a simple approach for monitoring bitter substances and investigating the mechanism of ligand-receptor interaction. In the experiment, the researchers used many compounds, for example, (2R,3R,4S,5R,6R)-2-(Acetoxymethyl)-6-(((2S,3S,4R,5R)-3,4-diacetoxy-2,5-bis(acetoxymethyl)tetrahydrofuran-2-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (cas: 126-14-7Related Products of 126-14-7).
(2R,3R,4S,5R,6R)-2-(Acetoxymethyl)-6-(((2S,3S,4R,5R)-3,4-diacetoxy-2,5-bis(acetoxymethyl)tetrahydrofuran-2-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (cas: 126-14-7) belongs to tetrahydrofuran derivatives. THF (Tetrahydrofuran) is a stable compound with relatively low boiling point and excellent solvency. THF can also be synthesized by catalytic hydrogenation of furan. This allows certain sugars to be converted to THF via acid-catalyzed digestion to furfural and decarbonylation to furan, although this method is not widely practiced. THF is thus derivable from renewable resources.Related Products of 126-14-7
Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem