Stereoselective Total Synthesis of 4-(S)-Hydroxy-5-(R)-octyldihydrofuran-2-one: Harvestmen Lactone was written by Desireddi, Janardana Reddi;Rao, Mora Mallikarjuna;Murahari, Kiran Kumar;Nimmareddy, Rajashekar Reddy;Mothe, Thirupathi;Lingala, Arun Kumar;Maiti, Bhimcharan;Manchal, Ravinder. And the article was included in ChemistrySelect in 2022.HPLC of Formula: 582-52-5 This article mentions the following:
A facile and stereoselective synthesis of Harvestmen lactone, 4-(S)-hydroxy-5-(R)-octyldihydrofuran-2-one, was accomplished in a linear synthetic approach over 14 steps with an overall yield of 10.1%. This total synthesis was carried out using a chiral pool approach from com. available D-glucose. The key reactions employed in this synthetic approach were Wittig reaction, Barton-McCombie deoxygenation and TEMPO-mediated radical oxidation In the experiment, the researchers used many compounds, for example, (3aR,5S,6S,6aR)-5-((R)-2,2-Dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol (cas: 582-52-5HPLC of Formula: 582-52-5).
(3aR,5S,6S,6aR)-5-((R)-2,2-Dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol (cas: 582-52-5) belongs to tetrahydrofuran derivatives. Tetrahydrofuran (THF), or oxolane, is mainly used as a precursor to polymers. Being polar and having a wide liquid range, THF is a versatile solvent. It is more basic than diethyl ether and forms stronger complexes with Li+, Mg2+, and boranes. It is a popular solvent for hydroboration reactions and for organometallic compounds such as organolithium and Grignard reagents.HPLC of Formula: 582-52-5
Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem