A novel model of molnupiravir against SARS-CoV-2 replication: accumulated RNA mutations to induce error catastrophe was written by Zhao, Yuxi;He, Gu;Huang, Wei. And the article was included in Signal Transduction and Targeted Therapy in 2021.Application of 2492423-29-5 The following contents are mentioned in the article:
A review. This article discusses about findings of a recent systematic biochem. anal. that proposed a two-step mechanism for molnupiravir-induced mutagenesis of coronavirus RNA. The experiments suggest a two-step mechanism in which molnupiravir induces SARS-CoV-2 RNA mutagenesis by forming stable M-G and M-A base pairs in the RdRp active site. Therefore, future studies should assess the potential long-term genotoxic side effects of molnupiravir. This study involved multiple reactions and reactants, such as ((2R,3S,4R,5R)-3,4-Dihydroxy-5-((Z)-4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl isobutyrate (cas: 2492423-29-5Application of 2492423-29-5).
((2R,3S,4R,5R)-3,4-Dihydroxy-5-((Z)-4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl isobutyrate (cas: 2492423-29-5) belongs to tetrahydrofuran derivatives. THF (Tetrahydrofuran) is a stable compound with relatively low boiling point and excellent solvency. Tetrahydrofuran (THF) is primarily used as a precursor to polymers including for surface coating, adhesives, and printing inks.Application of 2492423-29-5
Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem