Dhand, Abhay et al. published their research in Transplantation in 2022 | CAS: 2492423-29-5

((2R,3S,4R,5R)-3,4-Dihydroxy-5-((Z)-4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl isobutyrate (cas: 2492423-29-5) belongs to tetrahydrofuran derivatives. THF (Tetrahydrofuran) is water-miscible and has a low viscosity making it a highly versatile solvent used in a variety of industries. THF (Tetrahydrofuran) is also used as a starting material for the synthesis of poly(tetramethylene ether) glycol (PTMG), etc.Related Products of 2492423-29-5

Sotrovimab for Treatment of COVID-19 in Solid Organ Transplant Recipients was written by Dhand, Abhay;Okumura, Kenji;Wolfe, Kevin;Lobo, Stephen A.;Nog, Rajat;Keller, Marina;Bodin, Roxana;Singh, Nandita;Levine, Avi;Nabors, Christopher. And the article was included in Transplantation in 2022.Related Products of 2492423-29-5 The following contents are mentioned in the article:

Solid organ transplant recipients (SOTRs) may be at higher risk of developing severe coronavirus disease 2019 (COVID-19). Early use of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) monoclonal antibody in SOTRs provides a safe outpatient treatment option to reduce COVID-1 9-related risk of hospitalization and death. Sotrovimab is a recombinant human Ig-Gl-kappa monoclonal antibody that binds to a conserved epitope on the spike protein receptor-binding domain of SARS-CoV and SARS-CoV-2. Oral antiviral use is limited in SOTRs because of significant drug-drug interaction with nirmatrelvir/ritonavir and observed reduced efficacy of molnupiravir. Therefore, sotrovimab, based on its longer half-life and neutralizing activity against almost all the currently known coronavirus variants, potentially offers another safe and efficacious therapy for outpatient management of SOTRs with mild to moderate COVID-19. This study involved multiple reactions and reactants, such as ((2R,3S,4R,5R)-3,4-Dihydroxy-5-((Z)-4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl isobutyrate (cas: 2492423-29-5Related Products of 2492423-29-5).

((2R,3S,4R,5R)-3,4-Dihydroxy-5-((Z)-4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl isobutyrate (cas: 2492423-29-5) belongs to tetrahydrofuran derivatives. THF (Tetrahydrofuran) is water-miscible and has a low viscosity making it a highly versatile solvent used in a variety of industries. THF (Tetrahydrofuran) is also used as a starting material for the synthesis of poly(tetramethylene ether) glycol (PTMG), etc.Related Products of 2492423-29-5

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem