Day: November 21, 2022

Naniwa, Shimpei published the artcileVisible light-induced Minisci reaction through photoexcitation of surface Ti-peroxo species, Formula: C4H6O3, the publication is Catalysis Science & Technology (2021), 11(10), 3376-3384, database is CAplus.

Photocatalytic Minisci-type functionalization of pyridine with THF (THF) proceeded using hydrogen peroxide (H₂O₂) and a TiO₂ photocatalyst under acidic conditions. Under UV light (λ = 360 nm), the reaction selectivity based on pyridine (S_py) was >99% while the selectivity based on THF (S_THF) was low such as 19%. In contrast, under visible light (λ = 400 or 420 nm) S_py was similarly high (>99%) and S_THF was two times higher than that under UV light. A surface peroxo complex formed upon contact of hydrogen peroxide with the TiO₂ surface can be selectively photoexcited by visible light to inject the photoexcited electron to the conduction band of TiO₂. The electron can reduce H₂O₂ to a reactive oxygen species (ROS) and promote selectively the Minisci-type cross-coupling reaction between pyridinium ions and THF. A reaction test with a hole scavenger (methanol) evidenced that the hole oxidation of H₂O₂ under UV light was responsible for the lower selectivity, in other words, the higher selectivity under visible light would be due to suppression of the hole oxidation of H₂O₂. These results demonstrate a novel way to improve the selectivity of the photocatalytic cross-coupling reaction by using H₂O₂ as an oxidant with the photoexcitation of surface Ti-peroxo species on TiO₂.

Catalysis Science & Technology published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Formula: C4H6O3.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Sakatsume, Osamu published the artcileSolid phase synthesis of oligoribonucleotides by the phosphoramidite approach using 2′-O-1-(2-chloroethoxy)ethyl protection, Synthetic Route of 87865-78-9, the publication is Tetrahedron (1991), 47(41), 8717-28, database is CAplus.

The new protecting group, 1-(2-chloroethoxy)ethyl (Cee), has been employed for the protection of the 2′-OH groups of ribonucleoside residues in the synthesis of oligoribonucleotides by the phosphoramidite approach on a solid support, using the acid-labile 5′-O-dimethoxytrityl (DMTr) group. The Cee group is completely stable under the acidic conditions required to remove the 5′-terminal protecting groups in oligonucleotide synthesis on a solid support, and yet is easily removable under mild condition of acidic hydrolysis (pH 2.0) for the final unblocking step. The Cee-protected ribonucleoside 3′-phosphoramidite units were evaluated in the synthesis of homopolymers of cytidine, the box 9R and 9R’ sequences of Tetrahymena rRNA, and a leader sequence of phage Qβ-A protein mRNA. Procedures for the deprotection and purification of the synthetic oligoribonucleotides are also described.

Tetrahedron published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C26H45N5O7Si2, Synthetic Route of 87865-78-9.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Yin, Chunyan published the artcileStudy on the effect of potassium lactate additive on the combustion behavior and mainstream smoke of cigarettes, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one, the publication is Journal of Thermal Analysis and Calorimetry (2014), 115(2), 1733-1751, database is CAplus.

The influence of potassium lactate (PL) on the combustion behavior and semi-volatile compounds of tobacco during smoking is investigated in this study. The addition of PL showed no effect on the content of total particulate matter, nicotine-free dry particulate matter, puff number, and nicotine. Meanwhile, a 22.5 % increase in moisture content and 3 % decrease in CO content of mainstream smoke were observed when the added amount of PL was up to 2 %. The differential thermogravimetric curves indicated that PL decreased the maximum combustion rate and influenced the thermal degradation stage of tobacco by shifting the peak point of temperature to a higher value. The gas evolution profiles obtained from Fourier transform IR spectroscopy during combustion showed that PL could lower the CO and CO₂ yield, but did not affect the generation of CH₄ and carbonyl compounds A great variation in semi-volatile components of the mainstream smoke was also observed from the tobacco containing PL compared with the control. The comprehensive two-dimensional gas chromatog. coupled to time-of-flight mass spectrometry anal. showed that PL increased the yield of alcs., lactons, miscellaneous oxygenated compounds and amides, but decreased that of aldehydes, acids, pyrroles and pyrazines. A small added amount (0.2 %) of PL reduced the content of total semi-volatile substances, ketones, esters, phenols, hydrocarbons, pyridines, tobacco alkaloids, and nitrogenous compound However, the contents of these substances were not affected when the added amount was >0.2 %. PL bound the ash during combustion, thereby leading to the change of combustion behavior and certain smoke components.

Journal of Thermal Analysis and Calorimetry published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C17H19N3O6, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Luo, Changrong published the artcileCo-pyrolysis behavior of glucose, fructose and sucrose/proline mixtures, Quality Control of 19444-84-9, the publication is Yancao Keji (2014), 61-69, database is CAplus.

In order to understand the behavior and interaction of main sugars and amino acids in tobacco during cigarette combustion, the behaviors of glucose, fructose, sucrose and proline pyrolyzed independently or collectively were investigated by Py-GC/MS, the behaviors of co-pyrolysis and independent pyrolysis were analyzed and compared. The results showed that: 1) The co-pyrolysis of glucose, fructose and sucrose with proline impacted obvious influences on the formation of volatile compounds comparing with independent pyrolysis. When the ratio of sugars to proline was 5:1, 5-hydroxymethyl furfural formed in the process of co-pyrolysis were about 3.4%, 6.0% and 20.3% of that formed in the independent pyrolysis of glucose, fructose and sucrose, resp.; furfurals formed were about 5.9%, 2.0% and 6.3%, and levoglucosans were about 1.0%, 27.1% and 8.7%, resp. When the ratio of sugars to proline was 10:1, 5-hydroxymethyl furfurals formed in co-pyrolysis were about 35.5%, 30.0% and 81.3% of that formed in independent pyrolysis of glucose, fructose and sucrose, resp.; furfurals formed were about 29.9%, 11.3% and 22.5%, and levoglucosan were about 11.5%, 90.6% and 26.9%, resp. 2) The composition of sugar mixture and its ratio to proline significantly affected the formation of pyrolytic products, and the influence raised with the increase of proline content.

Yancao Keji published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Quality Control of 19444-84-9.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Zhu, Jiancai published the artcileAnalysis of volatile components of roasted beef flavor 7015, Formula: C5H10OS, the publication is Xiangliao Xiangjing Huazhuangpin (2012), 14-16, database is CAplus.

The applicability of headspace solid-phase microextraction (HS/SPME) combined with gas chromatog. and mass spectrometry (GC/MS) for determination of volatile components in roasted beef flavor was investigated in this paper. The results showed that 24 volatile components were identified, including carboxylic acids, aldehydes, phenolic compounds, heterocyclic compounds (pyrazine ring, thiazole ring) and alcs.

Xiangliao Xiangjing Huazhuangpin published new progress about 57124-87-5. 57124-87-5 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Thiol, name is 2-Methyl-3-tetrahydrofuranthiol, and the molecular formula is C4H6O3, Formula: C5H10OS.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Dai, Shuiping published the artcileAnalysis and simulation of volatile components of roasted beef, Formula: C5H10OS, the publication is Xiangliao Xiangjing Huazhuangpin (2010), 43-47, database is CAplus.

Applicability of headspace solid-phase microextraction (HS-SPME) combined with gas chromatog. and mass spectrometry (GC-MS) for determination of volatile components in roasted beef was investigated. The 42 volatile components were identified, including carboxylic acid compounds, aldehyde compounds, phenolic compounds, heterocyclic compounds (pyrazine ring, thiazole ring) and alcs. Based on GC-MS anal., realistic and coordinated roasted beef flavor was simulated using sensory anal. And its aroma profile was similar with the roasted beef determined up to 92.4% by electronic nose (E-nose).

Xiangliao Xiangjing Huazhuangpin published new progress about 57124-87-5. 57124-87-5 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Thiol, name is 2-Methyl-3-tetrahydrofuranthiol, and the molecular formula is C5H10OS, Formula: C5H10OS.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Ni, Zhi-Jing published the artcileAnalysis of key precursor peptides and flavor components of flaxseed derived Maillard reaction products based on iBAQ mass spectrometry and molecular sensory science, Recommanded Product: 2-Methyl-3-tetrahydrofuranthiol, the publication is Food Chemistry: X (2022), 100224, database is CAplus and MEDLINE.

Flaxseed derived Maillard reaction products (MRPs) have typical meaty flavor, but there is no report on comparison of their amino acids and peptides reactivity. The peptides and amino acids of flaxseed protein hydrolyzates were sep. collected by G-15 gel chromatog. Taste dilution anal. (TDA) showed that peptides-MRPs had high umami, mouthfulness, and continuity enhancement. Further, LC-MS/MS revealed that flaxseed protein hydrolyzates consumed 41 peptides after Maillard reaction. Particularly, DLSFIP (Asp-Leu-Ser-Phe-Ile-Pro) and ELPGSP (Glu-Leu-Pro-Gly-Ser-Pro) accounted for 42.22% and 20.41% of total consumption, resp. Aroma extract dilution anal. (AEDA) indicated that formation of sulfur-containing flavors was dependent on cysteine, while peptides were more reactive than amino acids for nitrogen-containing heterocycles. On the other hand, 11 flavor compounds with flavor dilution (FD) ≥ 64 were identified for flaxseed derived MRPs, such as 2-methylthiophene, 2-methyl-3-furanthiol, furfural, 2-furfurylthiol, 3-thiophenethiol, thieno[3,2-b] thiophene, 2,5-thiophenedicarboxaldehyde, 2-methylthieno[2,3-b] thiophene, 1-(2-methyl-3-furylthio)-ethanethiol, 2-methylthieno[3,2-b] thiophene, and bis(2-methyl-3-furyl)-disulfide. In addition, we further demonstrated the flavors formation mechanism of flaxseed derived MRPs.

Food Chemistry: X published new progress about 57124-87-5. 57124-87-5 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Thiol, name is 2-Methyl-3-tetrahydrofuranthiol, and the molecular formula is C5H10OS, Recommanded Product: 2-Methyl-3-tetrahydrofuranthiol.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Wang, Wen-peng published the artcileIsolation and identification of three anaerobic bacteria strains in Luzhou-flavor liquor and metabolites analysis, HPLC of Formula: 19444-84-9, the publication is Shipin Keji (2018), 43(2), 15-20, database is CAplus.

In this experiment, anaerobic bacteria were isolated from pit mud under anaerobic condition, and the metabolites were analyzed by GC-MS and through colony morphol. observation, Gram staining, spore staining, biochem. test, phospholipid fatty acid anal. and 16S rDNA identification. Three strains of bacteria were screened, resp. named as SJ-1, SJ-2 and SJ-3. It was obtained from the anal. and identification that SJ-1 is Bacillus liciusiformis, SJ-2 is Bacillus aerius, and SJ-3 is Clostridium butyricum subsp. The results of the fermentation products showed that the main products of the three strains such as butyric acid, n-butanol, acetic acid, 2,3-butanediol that are the skeletal components in the micro components of Luzhou-flavor liquor, Strain SJ-3 had good performance, and its yield of butyric acid was 202.56 mg/mL, indicating that the three strains play a pos. role in the production of flavor substances in the Luzhou-flavor liquor.

Shipin Keji published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C13H11NO, HPLC of Formula: 19444-84-9.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Chen, Zhuo published the artcileAcenaphtho[1,2-b]pyrrole-Based Selective Fibroblast Growth Factor Receptors 1 (FGFR1) Inhibitors: Design, Synthesis, and Biological Activity, Application of 2-Methyl-3-tetrahydrofuranthiol, the publication is Journal of Medicinal Chemistry (2011), 54(11), 3732-3745, database is CAplus and MEDLINE.

A novel series of acenaphtho[1,2-b]pyrrole derivatives as potent and selective inhibitors of fibroblast growth factor receptor 1 (FGFR1) were designed and synthesized. In silico target prediction revealed that tyrosine kinases might be the potential targets of the representative compound I, which was subsequently validated by ELISA for its selective and active FGFR1 inhibition of various tyrosine kinases. The structure-activity relationship (SAR) anal. aided by mol. docking simulation in the ATP-binding site demonstrated that acenaphtho[1,2-b]pyrrolecarboxylic acid esters are potent inhibitors of FGFR1 with IC₅₀ values ranging from 19 to 77 nM. Furthermore, these compounds exhibited favorable growth inhibition property against FGFR-expressing cancer cell lines with IC₅₀ values ranging from micromolar to submicromolar. Western blotting anal. showed that three of these compounds inhibited activation of FGFR1 and extracellular-signal regulated kinase 1/2 (Erk1/2).

Journal of Medicinal Chemistry published new progress about 57124-87-5. 57124-87-5 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Thiol, name is 2-Methyl-3-tetrahydrofuranthiol, and the molecular formula is C5H10OS, Application of 2-Methyl-3-tetrahydrofuranthiol.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Spanik, I. published the artcileA comparative study of various sample preparation procedures for characterization of organic compounds in brandy, SDS of cas: 19444-84-9, the publication is Uchenye Zapiski Kazanskogo Universiteta, Seriya Estestvennye Nauki (2014), 156(4), 8-28, database is CAplus.

This paper describes the composition of volatile compounds in 19 different wine distillates was studied by gas chromatog. (GC) coupled with flame ionization (FID) or mass-spectrometric (MS) detector. The studied samples were divided into two groups depending on the way of their production and geog. region. The effect of various sample treatment procedures on final composition of volatiles was investigated in details. The effectiveness of direct injection, headspace, solid phase extraction (SPE), solid phase microextraction (SPME) and liquid-liquid extraction (LLE) was compared. Moreover, the effect of exptl. conditions of preconcentration methods such as type of sorbent, temperature, time or solvent removal procedure was studied in details. The repeatability of particular sample preparation procedure was evaluated by comparison of peak areas for randomly selected compounds obtained from 4 parallel measurements. It was shown that the most suitable sample treatment procedure in terms of repeatability is SPE followed by direct injection and headspace. LLE and SPME provide higher variability of peak areas, thus utilization of internal standard for quantification is recommended. On the contrary, the most suitable sample treatment procedure in terms of the number of different type of compounds is liquid-liquid extraction into CH₂Cl₂. By this method, more than 240 compounds have been extracted from wine distillates produced by classical technol. Furthermore, SPME has shown different selectivity which allows one to determine compounds that could not be extracted by other studied sample preparation methods.

Uchenye Zapiski Kazanskogo Universiteta, Seriya Estestvennye Nauki published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C30H24BrCuN2P, SDS of cas: 19444-84-9.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem