Preparation of halonucleosides was written by Haga, Kazuko; Yoshikawa, Masaharu; Kato, Tetsuya. And the article was included in Bulletin of the Chemical Society of Japan in 1970.Synthetic Route of C10H12N4O4 The following contents are mentioned in the article:
5′-Chloro- (I), 5′-bromo- (II), and 5′-deoxy-5′-iodo-2′,3′-O-isopropylideneinosine (III) are prepared by the treatment of 2′,3′-O-isopropylideneinosine, in (EtO)3PO containing Ph3P, with CCl4, Br, BrCN, and iodine. Similarly, 5′-O-acetylinosine gives 9-(3-chloro-3-deoxy-β-D-xylofuranosyl)-hypoxanthine (IV). I, II, and III are not obtained when the (EtO)3PO is replaced by DMF. This study involved multiple reactions and reactants, such as 9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol (cas: 13146-72-0Synthetic Route of C10H12N4O4 ).
9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol (cas: 13146-72-0) belongs to tetrahydrofuran derivatives. Tetrahydrofuran (THF), or oxolane, is mainly used as a precursor to polymers. Being polar and having a wide liquid range, THF is a versatile solvent. THF can also be synthesized by catalytic hydrogenation of furan. This allows certain sugars to be converted to THF via acid-catalyzed digestion to furfural and decarbonylation to furan, although this method is not widely practiced. THF is thus derivable from renewable resources.Synthetic Route of C10H12N4O4
13146-72-0;9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol;The future of 13146-72-0;New trend of C10H12N4O4 ;function of 13146-72-0