Metabolism of 2-deoxy-2-fluoro-D-[3H]-glucose and 2-deoxy-2-fluoro-D-[3H]-mannose in yeast and chick embryo cells was written by Schmidt, Michael F. G.; Biely, Peter; Kratky, Zdenek; Schwarz, Ralph T.. And the article was included in European Journal of Biochemistry on June 15,1978.Related Products of 67341-43-9 The following contents are mentioned in the article:
2-Deoxy-2-fluoro-D-glucose-3H and 2-deoxy-2-fluoro-D-mannose-3H were prepared by tritiation of the corresponding unlabeled 2-fluoro sugars. The tritiated 2-fluoro sugars were phosphorylated and activated by UTP and by GTP to yield UDP-2-deoxy-2-fluoro-D-glucose-3H, UDP-2-deoxy-2-fluoro-D-mannose-3H, GDP-2-deoxy-2-fluoro-D-glucose-3H, and GDP-2-deoxy-2-fluoro-D-mannose-3H in yeast and chick embryo cells. The nucleotide derivatives were also labeled in the nucleotide moiety by feeding the cells with uridine-14C or guanosine-14C in the presence of unlabeled 2-fluoro sugar. No evidence was obtained for metabolic steps in which the 6-C chain of 2-fluoro sugars was not preserved. No epimerization of the label to 2-deoxy-2-fluoro-D-galactose-3H was observed by radioactive gas-liquid chromatog. of the enzymic cleavage products of the different 2-fluoro sugar metabolites isolated from either cell type. Yeast and chick embryo cells both incorporate a 2-deoxy-2-fluoro-D-glucose-3H and 2-deoxy-2-fluoro-D-mannose-3H specifically into glycoproteins, although this incorporation was very low when compared to the incorporation of 2-deoxy-D-glucose-3H. This study involved multiple reactions and reactants, such as Uridine 5′-(trihydrogen diphosphate) P’-(2-deoxy-2-fluoro-α-D-glucopyranosyl) ester (cas: 67341-43-9Related Products of 67341-43-9).
Uridine 5′-(trihydrogen diphosphate) P’-(2-deoxy-2-fluoro-α-D-glucopyranosyl) ester (cas: 67341-43-9) belongs to tetrahydrofuran derivatives. Solid acid catalysis, and the advantages often associated with their use, have been proved equally efficient for the synthesis of tetrahydrofurans or furans. THF (Tetrahydrofuran) is also used as a starting material for the synthesis of poly(tetramethylene ether) glycol (PTMG), etc.Related Products of 67341-43-9
67341-43-9;Uridine 5′-(trihydrogen diphosphate) P’-(2-deoxy-2-fluoro-α-D-glucopyranosyl) ester;The future of 67341-43-9;New trend of C15H23FN2O16P2 ;function of 67341-43-9