Inhibition of axenically grown Entamoeba histolytica by purine nucleoside analogs and actions of natural nucleosides was written by Das, S. R.; Baer, H. P.. And the article was included in Tropical Medicine and Parasitology on September 30,1991.Safety of 9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol The following contents are mentioned in the article:
The effects of the nucleoside analogs tubercidin, nebularin, formycin B and 3′-deoxyinosine on axenically grown Entamoeba histolytica were tested. Both tubercidin and nebularin showed pronounced inhibitory action, 50% of growth inhibition (IC50) being obtained at 0.14 and 0.82 μM, resp. Formycin B and 3′-deoxyinosine were essentially inactive or weakly active at concentrations above 10 μM. Natural nucleosides, including adenosine, inosine, guanosine, thymidine, uridine and cytidine caused no significant effects at concentrations of 0.01-1 μM; however, significant inhibitory action was observed at or above 10 μM with cytidine and thymidine. The exploration of cytotoxic nucleosides as antiamebal drugs is of continued interest. This study involved multiple reactions and reactants, such as 9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol (cas: 13146-72-0Safety of 9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol).
9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol (cas: 13146-72-0) belongs to tetrahydrofuran derivatives. THF (Tetrahydrofuran) is water-miscible and has a low viscosity making it a highly versatile solvent used in a variety of industries. Tetrahydrofuran (THF) is primarily used as a precursor to polymers including for surface coating, adhesives, and printing inks.Safety of 9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol
13146-72-0;9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol;The future of 13146-72-0;New trend of C10H12N4O4 ;function of 13146-72-0