Month: October 2022

Alvarez, Alejandro; Gutierrez, Alejandra; Ramirez, Cristina; Cuenca, Frank; Bolivar, German published an article on January 31 ,2022. The article was titled 《Aroma compounds produced by liquid fermentation with Saccharomyces cerevisiae and Zygosaccharomyces rouxii from castor oil through cell permeabilization》, and you may find the article in Biocatalysis and Agricultural Biotechnology.COA of Formula: C4H6O3 The information in the text is summarized as follows:

The use of microorganisms to produce aroma mols. is growing in the flavor and fragrance industries due to the increased market for natural products. In this study, the effect of the type of microorganism, and cellular permeabilization on the production of aroma mols. from castor oil by liquid fermentation with yeasts, was assessed for possible application in the production of natural flavors. Different treatments were assessed with a three-way factorial design (type of microorganism, cell permeabilization and amount of castor oil), the aroma profile was analyzed using gas chromatog. with mass spectrometry (GC-MS), and the treatments were classified by principal component anal. (PCA). The results showed a significant effect of the yeast S. cerevisiae and Z. rouxii, the permeabilization treatment, and the amount of castor oil in the production of aroma compounds (p < 0.05). The mols. 4-hydroxy-2-pentenoic acid γ-lactone, Me pyruvate, 2,3,4-trimethyl-3-pentanol, and δ-decalactone were affected by all the factors. The production of metabolites increased with the permeabilization treatments for certain mols. like ethanol and organic acids, whereas the generation of others decreased. The use of these microorganisms and cell permeabilization are promising approaches for producing mols. with applications in natural flavors. In addition to this study using 3-Hydroxydihydrofuran-2(3H)-one, there are many other studies that have used 3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9COA of Formula: C4H6O3) was used in this study.

3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9) is a 5-membered cyclic ester. It was obtained via tin-conversion of biomass-derived 1,3-dihydroxyacetone (DHA) and formaldehyde. And it may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis.COA of Formula: C4H6O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Hu, Fang-Peng; Zhang, Xue-Guo; Wang, Meng; Wang, He-Song; Huang, Guo-Sheng published an article in 2021. The article was titled 《Synthesis of oxazolidinones through ring-opening and annulation of vinylene carbonate with 2-pyrrolyl/indolylanilines under Rh(III) catalysis》, and you may find the article in Chemical Communications (Cambridge, United Kingdom).Electric Literature of C6H12O3 The information in the text is summarized as follows:

Herein, a rhodium-catalyzed C-H functionalization and subsequent intramol. ring-opening/cyclization of vinylene carbonate with o-aminophenyl pyrroles and indoles, e.g. I (R1 = H, 3-Me, 4-F, 5-MeO, etc.; R2 = H, 4-Me, 5-F, etc.), which leads to fused oxazolidinones, e.g. II, in moderate to good yields is reported. In this transformation, vinylene carbonate only eliminates one oxygen atom rather than -CO3 or CO2. Furthermore, some control experiments were conducted to elucidate the reaction mechanism. In the part of experimental materials, we found many familiar compounds, such as 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Electric Literature of C6H12O3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Electric Literature of C6H12O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Wang, Yinghao; Wang, Yongxing; Lu, Yaowei; Cao, Qiue; Fang, Wenhao published an article in 2021. The article was titled 《Efficient hydrogenation of 5-hydroxymethylfurfural using a synergistically bimetallic Ru-Ir/C catalyst》, and you may find the article in Chemical Communications (Cambridge, United Kingdom).Computed Properties of C6H12O3 The information in the text is summarized as follows:

Activated charcoal-dispersed Ru-Ir alloy nanoparticles (ca. 2.2 nm) are a selective and reusable hydrogenation catalyst for the conversion of 5-hydroxymethylfurfural to valuable liquid biofuel. A 99% yield to 2,5-dimethylfuran is achieved at only 120°C. An acceleration in the reduction of substrate and intermediates is observed due to the synergistic effect between the Ru and Ir species. In the experimental materials used by the author, we found 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Computed Properties of C6H12O3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Computed Properties of C6H12O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Fathalinejad, Samin; Taarning, Esben; Christensen, Peter; Christensen, Jan H. published an article in Journal of Analytical and Applied Pyrolysis. The title of the article was 《Chemical composition analysis of carbohydrate fragmentation products》.Quality Control of 3-Hydroxydihydrofuran-2(3H)-one The author mentioned the following in the article:

Fragmentation of simple sugars, using fluidized thermal bed cracking, results in a mixture that contains a variety of polar oxygenated compounds, some yet unknown to the industries. This lack of understanding of the product composition, hinders the downstream processes in conversion of sugars to useful chems. The aim of this study was fourfold: to develop a GC-MS identification workflow for carbohydrate fragmentation compounds, to build a library of compounds detected by five GC-MS methods including liquid injection, liquid-liquid extraction, static headspace, solid-phase microextraction and derivatization, to investigate and compare the compound coverage of the five methods, and finally investigate possible reaction pathways for some of the analytes in the mixture The anal. was done on a mixture of seven representative sugar fragmentation samples. The identification workflow was based on mass spectral match factors (>80%), retention indexes and anal. standards A total of 389 compounds were detected, out of which, 46 compounds were fully identified (through confirmatory anal. of anal. standards), 87 were tentatively identified (spectral match factors above 80%), 71 were un-identified with spectral match factors of below 80% and 185 were discarded (contaminants in blanks, etc.). The production pathway for some of the identified compounds in the sugar conversion mixtures were also discussed. In conclusion, solid-phase microextraction detected the highest number of analytes (93), mostly volatile organic compounds and the derivatization GC-MS technique detected the lowest number of analytes (19) but was the only method to detect the largest mols. (C6-C12) in size. This library of CF products can be used as a suspect-screening database for other biomass fragmentation mixtures3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9Quality Control of 3-Hydroxydihydrofuran-2(3H)-one) was used in this study.

3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9) is a 5-membered cyclic ester. It was obtained via tin-conversion of biomass-derived 1,3-dihydroxyacetone (DHA) and formaldehyde. And it may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis.Quality Control of 3-Hydroxydihydrofuran-2(3H)-one

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Electric Literature of C4H6O3On September 18, 2019 ,《Enantioconvergent Alkylations of Amines by Alkyl Electrophiles: Copper-Catalyzed Nucleophilic Substitutions of Racemic α-Halolactams by Indoles》 was published in Journal of the American Chemical Society. The article was written by Bartoszewicz, Agnieszka; Matier, Carson D.; Fu, Gregory C.. The article contains the following contents:

Transition-metal catalysis has the potential to address shortcomings in the classic SN2 reaction of an amine with an alkyl electrophile, both with respect to reactivity and to enantioselectivity. The authors describe the development of a user-friendly method (reaction at room temperature, with com. available catalyst components) for the enantioconvergent nucleophilic substitution of racemic secondary alkyl halides (α-iodolactams) by indoles. Mechanistic studies are consistent with the formation of a copper(I)-indolyl complex that reacts at different rates with the two enantiomers of the electrophile, which interconvert under the reaction conditions (dynamic kinetic resolution). This study complements earlier work on photoinduced enantioconvergent N-alkylation, supporting the premise that this important challenge can be addressed by a range of strategies. The experimental part of the paper was very detailed, including the reaction process of 3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9Electric Literature of C4H6O3)

3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9) may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis. It may be employed as starting reagent in the synthesis of enantiomerically pure orthogonally protected δ-azaproline, via Mitsunobu reaction.Electric Literature of C4H6O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

In 2019,Bulletin of the Chemical Society of Ethiopia included an article by Gullapelli, Kumaraswamy; Brahmeshwari, G.; Ravichander, M.. HPLC of Formula: 696-59-3. The article was titled 《A facile synthesis of 1-aryl pyrroles by Clauson-Kaas reaction using oxone as a catalyst under microwave irradiation》. The information in the text is summarized as follows:

A new and efficient methodol. to synthesize N-substituted pyrrole derivatives I (R = Ph, 4-chloro-2-nitrophenyl, benzenesulfonyl, etc.) by Clauson-Kaas reaction employing oxone as catalyst was developed. The transformation was performed in acetonitrile under microwave irradiation This procedure has several advantages such as high yield, clean product formation, and short reaction time.2,5-Dimethoxytetrahydrofuran(cas: 696-59-3HPLC of Formula: 696-59-3) was used in this study.

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.HPLC of Formula: 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Formula: C6H12O3In 2022 ,《A solvent-free manganese(II) -catalyzed Clauson-Kaas protocol for the synthesis of N-aryl pyrroles under microwave irradiation》 appeared in Journal of Heterocyclic Chemistry. The author of the article were Rohit, Kizhakkekuttu Radhakrishnan; Meera, Gopinadh; Anilkumar, Gopinathan. The article conveys some information:

The first manganese-catalyzed modified Clauson-Kaas reaction for N-substituted pyrroles I (R = Ph, 2-bromo-4-methylphenyl, 1,3-benzothiazol-2-yl, etc.) synthesis using 2,5-dimethoxytetrahydrofuran with variously substituted aromatic amines RNH2 has been developed (up to 89% yield). This interesting neat strategy is free from additives including co-catalysts, ligands, and acids. Relatively low cost, environmentally benign, and handy Mn(NO3)2.4H2O is employed as the catalyst under microwave conditions with a very short reaction time (20 min). The above qualities attest to the green nature of this reaction. In the part of experimental materials, we found many familiar compounds, such as 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Formula: C6H12O3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Formula: C6H12O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

《Anti-quorum sensing and antibiofilm potential of 1,8-cineole derived from Musa paradisiaca against Pseudomonas aeruginosa strain PAO1》 was written by Karuppiah, Vijayakumar; Thirunanasambandham, Ramanathan; Thangaraj, Gunasekaran. Related Products of 19444-84-9 And the article was included in World Journal of Microbiology & Biotechnology on April 30 ,2021. The article conveys some information:

Abstract: Pseudomonas aeruginosa is one of the vulnerable opportunistic pathogens associated with nosocomial infections, cystic fibrosis, burn wounds and surgical site infections. Several studies have reported that quorum sensing (QS) systems are controlled the P. aeruginosa pathogenicity. Hence, the targeting of QS considered as an alternative approach to control P. aeruginosa infections. This study aimed to evaluate the anti-quorum sensing and antibiofilm inhibitory potential of Musa paradisiaca against Chromobacterium violaceum (ATCC 12472) and Pseudomonas aeruginosa. The methanol extract of M. paradisiacsa exhibits that better antibiofilm potential against P. aeruginosa. Then, the crude methanol extract was subjected to purify by column chromatog. and collected the fractions. The mass-spectrometric anal. of a methanol extract of M. paradisiaca revealed that 1,8-cineole is the major compounds 1, 8-cineole significantly inhibited the QS regulated violacein production in C. violaceum. Moreover, 1,8-cineole significantly inhibited the QS mediated virulence production and biofilm formation of P. aeruginosa without affecting their growth. The real-time PCR anal. showed the downregulation of autoinducer synthase and transcriptional regulator genes upon 1,8-cineole treatment. The findings of the present study strongly suggested that metabolite of M. paradisiaca impedes P. aeruginosa QS system and associated virulence productions. In the part of experimental materials, we found many familiar compounds, such as 3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9Related Products of 19444-84-9)

3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9) may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis. It may be employed as starting reagent in the synthesis of enantiomerically pure orthogonally protected δ-azaproline, via Mitsunobu reaction.Related Products of 19444-84-9

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

The author of 《Fluorinated iminophosphonates bearing stereodirecting phenylethyl group in synthesis of biorelevant scalemic aminophosphonates》 were Stanko, Oleg V.; Rassukana, Yuliya V.; Onys’ko, Petro P.. And the article was published in Phosphorus, Sulfur and Silicon and the Related Elements in 2019. Recommanded Product: 2,5-Dimethoxytetrahydrofuran The author mentioned the following in the article:

Diastereoselective reduction of α-(poly)fluoroalkylated iminophosphonates, bearing stereodirecting phenylethyl group at the nitrogen atom, produces diastereomeric N-(α-phenylethyl) polyfluoroalkylphosphonates. Separation and N-deprotection affords (S) and (R) α-amino polyfluoroalkylphosphonates. The latter react with 2,5-dimethoxytetrahydrofuran to give optically pure polyfluoroalkylphosphonates incorporating 1-pyrrolyl group in α-position. The results came from multiple reactions, including the reaction of 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Recommanded Product: 2,5-Dimethoxytetrahydrofuran)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Recommanded Product: 2,5-Dimethoxytetrahydrofuran

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

The author of 《Photochemical synthesis of π-extended ullazine derivatives as new electron donors for efficient conjugated D-A polymers》 were Miao, Dandan; Aumaitre, Cyril; Morin, Jean-Francois. And the article was published in Journal of Materials Chemistry C: Materials for Optical and Electronic Devices in 2019. Reference of 2,5-Dimethoxytetrahydrofuran The author mentioned the following in the article:

We report the synthesis of π-extended ullazine derivatives annulated with either electron-poor pyridine or electron-rich thiophene units through a metal-free, photochem. cyclodehydrochlorination (CDHC) reaction. The strongest electron-donor derivative, 7-tetradecylthieno[3′,2′:7,8]indolizino[6,5,4,3-ija]thieno[2,3-c]quinolone, was copolymerized with electron-deficient thienopyrroledione (TPD), isoindigo (IID), and diketopyrrolopyrrole (DPP) derivatives to provide three donor-acceptor conjugated polymers (D-A CPs). Their photophys., electrochem. and photovoltaic (PV) properties were investigated. The polymers showed broad UV-vis-NIR absorption bands with λmax values of 612 nm, 698 nm, 788 nm in chloroform and exhibited optical bandgap (Eoptg) of 1.58 eV, 1.41 eV, 1.24 eV measured as films. Inverted bulk heterojunction polymer solar cells (BHJ-PSCs) were fabricated using these polymers as host and light-harvesting materials. The device based on P3:PC70BM blends shows the best power conversion efficiency (PCE) of 2.23% (Voc = 0.55 V, Jsc = 7.86 mA cm-2, FF = 52%). These promising results demonstrate that π-extended ullazine derivatives can be used as electron-rich building blocks for the construction of D-A CPs for efficient PSCs applications. The results came from multiple reactions, including the reaction of 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Reference of 2,5-Dimethoxytetrahydrofuran)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Reference of 2,5-Dimethoxytetrahydrofuran

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem