Ueno, Masaharu; Huang, Yi-Yong; Yamano, Akihito; Kobayashi, Shu published the artcile< Revised Stereochemistry of Ceramide-Trafficking Inhibitor HPA-12 by X-ray Crystallography Analysis>, COA of Formula: C9H15NO4, the main research area is crystal mol structure ceramide trafficking inhibitor HPA; ceramide trafficking inhibitor preparation MSBAR.
In response to Berkes’s report revising the stereochem. of HPA-12, an important ceramide-trafficking inhibitor that was discovered and synthesized and its stereochem. determined in 2001, the synthesis and the stereochem. were reinvestigated. A large-scale synthetic method for HPA-12 based on a Zn-catalyzed asym. Mannich-type reaction in water was developed. Single crystals of HPA-12 for X-ray crystallog. anal. were obtained from Et propionate/n-hexane, and the stereochem. was definitely determined to be 1R,3S, consistent with Berkes’s revised structure.
Organic Letters published new progress about Conformation. 137105-97-6 belongs to class tetrahydrofurans, and the molecular formula is C9H15NO4, COA of Formula: C9H15NO4.
Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem