Day: October 19, 2022

In 2022,Gao, Anjiang; Wang, Yao; Lin, Guiying; Li, Bin; Hu, Xun; Huang, Yong; Zhang, Shu; Zhang, Hong published an article in Renewable Energy. The title of the article was 《Volatile-char interactions during biomass pyrolysis: Reactor design toward product control》.Category: tetrahydrofurans The author mentioned the following in the article:

This paper proposes a novel reactor featuring controllable adjustment of volatile-char interactions to investigate the pyrolysis of poplar wood and corresponding products. Controllable adjustment of volatile-char interactions enables the selective production of pyrolysis products. The oxygen content in biochar nearly disappears with the reduction of volatile-char interactions and the pore structure of biochar is improved after the interactions being intensified. Moreover, as the interactions reduce, the bio-oil yield increases by 1.23 times, and the outputs of acetic acid and phenols in the bio-oil exhibit decreasing trends, while that of levoglucosan is improved by nearly 4.5 times. Furthermore, the average mol. weight of bio-oil decreases from 786 to 322 g/mol with the continuous intensification of volatile-char interactions. It concludes that the controllable adjustment of volatile-char interactions plays a vital role in regulating the distribution of pyrolysis products and is of great importance to the production of light oil.2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Category: tetrahydrofurans) was used in this study.

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Category: tetrahydrofurans

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

In 2021,Plants included an article by Langa-Lomba, Natalia; Sanchez-Hernandez, Eva; Buzon-Duran, Laura; Gonzalez-Garcia, Vicente; Casanova-Gascon, Jose; Martin-Gil, Jesus; Martin-Ramos, Pablo. Product Details of 19444-84-9. The article was titled 《Activity of Anthracenediones and Flavoring Phenols in Hydromethanolic Extracts of Rubia tinctorum against Grapevine Phytopathogenic Fungi》. The information in the text is summarized as follows:

In this work, the chem. composition of Rubia tinctorum root hydromethanolic extract was analyzed by GC-MS, and over 50 constituents were identified. The main phytochems. were alizarin-related anthraquinones and flavoring phenol compounds The antifungal activity of this extract, alone and in combination with chitosan oligomers (COS) or with stevioside, was evaluated against the pathogenic taxa Diplodia seriata, Dothiorella viticola and Neofusicoccum parvum, responsible for the so-called Botryosphaeria dieback of grapevine. In vitro mycelial growth inhibition tests showed remarkable activity for the pure extract, with EC50 and EC90 values as low as 66 and 88 μg·mL-1, resp. Nonetheless, enhanced activity was attained upon the formation of conjugate complexes with COS or with stevioside, with synergy factors of up to 5.4 and 3.3, resp., resulting in EC50 and EC90 values as low as 22 and 56 μg·mL-1, resp. The conjugate with the best performance (COS-R. tinctorum extract) was then assayed ex situ on autoclaved grapevine wood against D. seriata, confirming its antifungal behavior on this plant material. Finally, the same conjugate was evaluated in greenhouse assays on grafted grapevine plants artificially inoculated with the three aforementioned fungal species, resulting in a significant reduction in the infection rate in all cases. This natural antifungal compound represents a promising alternative for developing sustainable control methods against grapevine trunk diseases. In addition to this study using 3-Hydroxydihydrofuran-2(3H)-one, there are many other studies that have used 3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9Product Details of 19444-84-9) was used in this study.

3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9) is a 5-membered cyclic ester. It was obtained via tin-conversion of biomass-derived 1,3-dihydroxyacetone (DHA) and formaldehyde. And it may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis.Product Details of 19444-84-9

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Wu, Haijun; Li, Xinlong; Zhang, Quan; Zhang, Kai; Xu, Xia; Xu, Jian published an article in Renewable Energy. The title of the article was 《Promoting the conversion of poplar to bio-oil based on the synergistic effect of alkaline hydrogen peroxide》.SDS of cas: 19444-84-9 The author mentioned the following in the article:

The synergistic catalysis effect of NaOH and H2O2 on the hydrothermal liquefaction (HTL) of poplar was investigated and compared to the NaOH or H2O2 catalyzed HTL at different temperatures and 30 min residence time. GC-MS, GPC, FT-IR, HPLC and TGA were used to comprehensively characterize the phys. and chem. properties of liquefied products (bio-oil, lignin and solid residue). The results showed that the highest total bio-oil yield (70.65%) was obtained at 280°C with NaOH (35 g/L)/H2O2 (30 g/L) as catalysts. The average mol. weight and polydispersity index (PDI) were found to be lower compared to that from other conditions. As the NaOH concentration was increased, the bio-oil yield was improved. The concentration of H2O2 for the optimal synergistic effect was observed to be 30 g/L. GC-MS anal. showed that the bio-oil obtained by NaOH (35 g/L)/H2O2 (30 g/L) was characterized with the lowest N content. The synergistic effect promoted the higher production selectivity of o-xylene and p-xylene in the bio-oil. After reading the article, we found that the author used 3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9SDS of cas: 19444-84-9)

3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9) is a 5-membered cyclic ester. It was obtained via tin-conversion of biomass-derived 1,3-dihydroxyacetone (DHA) and formaldehyde. And it may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis.SDS of cas: 19444-84-9

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Nicolai, Alice; Madia, Valentina Noemi; Messore, Antonella; De Vita, Daniela; De Leo, Alessandro; Ialongo, Davide; Tudino, Valeria; Tortorella, Elisabetta; Scipione, Luigi; Taurone, Samanta; Pergolizzi, Tiziano; Artico, Marco; Di Santo, Roberto; Costi, Roberta; Scarpa, Susanna published their research in Pharmaceuticals in 2021. The article was titled 《Anti-tumoral effects of a (1H-pyrrol-1-yl)methyl-1Hbenzoimidazole carbamate ester derivative on head and neck squamous carcinoma cell lines》.Product Details of 696-59-3 The article contains the following contents:

Nocodazole is an antineoplastic agent that exerts its effects by depolymerizing microtubules. Herein we report a structural analog of nocodazole, a (1H-pyrrol-1-yl)methyl-1H-benzoimidazole carbamate ester derivative, named RDS 60. We evaluated the antineoplastic properties of RDS 60 in two human head and neck squamous cell carcinoma (HNSCC) cell lines and we found that this compound significantly inhibited replication of both HNSCC cell lines without inducing any important cytotoxic effect on human dermal fibroblasts and human keratinocytes. The treatment of HNSCC cell lines with 1 μM RDS 60 for 24 h stopped development of normal bipolar mitotic spindles and, at the same time, blocked the cell cycle in G2/M phase together with cytoplasmic accumulation of cyclin B1. Consequently, treatment with 2 μM RDS 60 for 24 h induced the activation of apoptosis in both HNSCC cell lines. Addnl., RDS 60 was able to reverse the epithelial-mesenchymal transition and to inhibit cell migration and extracellular matrix infiltration of both HNSCC cell lines. The reported results demonstrate that this compound has a potent effect in blocking cell cycle, inducing apoptosis and inhibiting cell motility and stromal invasion of HNSCC cell lines. Therefore, the ability of RDS 60 to attenuate the malignancy of tumor cells suggests its potential role as an interesting and powerful tool for new approaches in treating HNSCC. In the part of experimental materials, we found many familiar compounds, such as 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Product Details of 696-59-3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Product Details of 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Willkomm, Janina; Bouzidi, Sara; Bertin, Erwan; Birss, Viola I.; Piers, Warren E. published their research in ACS Catalysis in 2021. The article was titled 《Aqueous CO2 Reduction by a Re(bipyridine)-polypyrrole Film Deposited on Colloid-Imprinted Carbon》.Name: 2,5-Dimethoxytetrahydrofuran The article contains the following contents:

Herein, we report a [Re(bipyridine)]-carbon hybrid material for efficient and selective CO2 to CO conversion in water. The Re catalyst was incorporated into a nanoporous colloid-imprinted carbon (CIC) powder by an electrochem. polymerization method. Uniform [Re(bipyridine)]-containing polymer films were formed on the carbon surface, where the catalyst-polymer loading could be controlled by varying the polymerization parameters. Thorough pre- and post-catalysis characterization confirmed the integrity of the [Re(bpy)] CO2 reduction catalyst. CIC|poly[Re] electrodes reduced CO2 to CO in 0.5 M CO2-saturated KHCO3 electrolyte solution at Eappl. = -0.66 V vs. reversible hydrogen electrode (RHE) (η = 550 mV), with initial Faradaic efficiencies for CO formation (FECO) between 88 and 100%. Higher catalyst loadings generally yielded higher FECO and better long-term stability under catalytic conditions, producing CO and maintaining selectivity of above 70% for a period of at least 24 h for the hybrid material with the highest [Re(bipyridine)] polymer loading. While electrochem. analyses suggested some electron and mass transport issues on shorter timescales, these were not confirmed in long-term electrolysis. Our work highlights the great applicability of (electro)polymerization techniques in combination with nanoporous CIC to prepare hybrid materials for energy conversion.2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Name: 2,5-Dimethoxytetrahydrofuran) was used in this study.

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Name: 2,5-Dimethoxytetrahydrofuran

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Tian, Run; Liang, Zhi-Qun; Wang, Yong; Zeng, Nian-Kai published an article in 2022. The article was titled 《Analysis of aromatic components of two edible mushrooms, Phlebopus portentosus and Cantharellus yunnanensis using HS-SPME/GC-MS》, and you may find the article in Results in Chemistry.COA of Formula: C6H12O3 The information in the text is summarized as follows:

A headspace solid-phase microextraction (HS-SPME) coupled with gas chromatog.-mass spectrometry (GC-MS) was used to evaluate the profile of the volatile components that accounted for the aroma of two edible mushrooms, viz. Phlebopus portentosus and Cantharellus yunnanensis. There were 51 and 69 volatile compounds identified from P. portentosus and C. yunnanensis, resp. These compounds were mainly acids, hydrocarbons, ketones, esters, aldehydes, and alcs., of which acetic acid was most abundant among these volatile components. Onanoic acid, 9-oxo-, Me ester, 2-pentyl-furan, and 5, 6-dihydro-2-pyranone were discovered in the mushrooms for the first time, and the volatile compounds of C. yunnanensis was also investigated for the first time. In addition, the volatile compounds of P. portentosus and C. yunnanensis were analyzed by principal components anal. (PCA). The findings reveal the differences among samples and provide the basic data for the chemotaxonomy in studying P. portentosus and C. yunnanensis. The experimental part of the paper was very detailed, including the reaction process of 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3COA of Formula: C6H12O3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.COA of Formula: C6H12O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

The author of 《Unexpected activated carbon-catalyzed pyrrolo[1,2-a]quinoxalines synthesis in water》 were Sun, Qi; Liu, Liyan; Yang, Yu; Zha, Zhenggen; Wang, Zhiyong. And the article was published in Chinese Chemical Letters in 2019. Application In Synthesis of 2,5-Dimethoxytetrahydrofuran The author mentioned the following in the article:

An interesting and recyclable activated carbon/water catalytic system for efficient synthesis of pyrrolo[1,2-a]quinoxaline derivatives was developed. The intramol. C-N and C-C bond was easily constructed in water under mild condition. This reaction featured a broad substrate scope, a good tolerance to water and air, metal-free, additive-free and redox reagent-free. In the part of experimental materials, we found many familiar compounds, such as 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Application In Synthesis of 2,5-Dimethoxytetrahydrofuran)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Application In Synthesis of 2,5-Dimethoxytetrahydrofuran

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

《A synthetic protocol for (-)-ketorolac; development of asymmetric gold(I)-catalyzed cyclization of allyl alcohol with pyrrole ring core》 was written by Sasaki, Ikuo; Yamasaki, Naoto; Kasai, Yusuke; Imagawa, Hiroshi; Yamamoto, Hirofumi. Electric Literature of C6H12O3 And the article was included in Tetrahedron Letters in 2020. The article conveys some information:

An asym. synthesis of (-)- and (+)-ketorolac was achieved with 89% ee using a novel Friedel-Crafts (FC) type C-C bond forming cyclization of an allyl alc. containing a pyrrole ring core in the presence of a bimetallic gold(I) salt complex prepared from a 2:2:1 combination of AuCl·SMe2, AgOTf and chiral Quinaphos. In the experiment, the researchers used many compounds, for example, 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Electric Literature of C6H12O3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Electric Literature of C6H12O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

SDS of cas: 696-59-3In 2020 ,《Pyrrolo[1,2-a]quinoxalines: Insulin Mimetics that Exhibit Potent and Selective Inhibition against Protein Tyrosine Phosphatase 1B》 appeared in ChemMedChem. The author of the article were Garcia-Marin, Javier; Griera, Mercedes; Sanchez-Alonso, Patricia; Di Geronimo, Bruno; Mendicuti, Francisco; Rodriguez-Puyol, Manuel; Alajarin, Ramon; de Pascual-Teresa, Beatriz; Vaquero, Juan J.; Rodriguez-Puyol, Diego. The article conveys some information:

PTP1B dephosphorylates insulin receptor and substrates to modulate glucose metabolism This enzyme is a validated therapeutic target for type 2 diabetes, but no current drug candidates have completed clin. trials. Pyrrolo[1,2-a]quinoxalines substituted at positions C1-C4 and/or C7-C8 were found to be nontoxic to cells and good inhibitors in the low- to sub-micromolar range, with the 4-benzyl derivative being the most potent inhibitor (0.24 μm). Some analogs bearing chlorine atoms at C7 and/or C8 kept potency and showed good selectivity compared to TCPTP (selectivity index >40). The most potent inhibitors behaved as insulin mimetics by increasing glucose uptake. The 4-benzyl derivative inhibited insulin receptor substrate 1 and AKT phosphorylation. Mol. docking and mol. dynamics simulations supported a putative binding mode for these compounds to the allosteric α3/α6/α7 pocket, but inconsistent results in enzyme inhibition kinetics were obtained due to the high tendency of these inhibitors to form stable aggregates. Computational calculations supported the druggability of inhibitors. In the experiment, the researchers used many compounds, for example, 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3SDS of cas: 696-59-3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.SDS of cas: 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem