Day: October 19, 2022

《Copper-Catalyzed Synthesis of Alkyl-Substituted Pyrrolo[1,2-a]quinoxalines from 2-(1H-Pyrrol-1-yl)anilines and Alkylboronic Acids》 was published in Synlett in 2020. These research results belong to Guan, Xin; Yan, Rulong. Recommanded Product: 2,5-Dimethoxytetrahydrofuran The article mentions the following:

A radical pathway for the construction of pyrrolo[1,2-a]quinoxalines I (R1 = H, 7-Me, 7-F, etc.; R2 = Me, Et, n-Pr, n-Bu, i-Pr; X = C, N) by using 2-(1H-pyrrol-1-yl)anilines and alkylboronic acids has been developed. Features of this process include Cu catalysis, readily accessible starting materials, and simple operations. Alkylboronic acids are used for the construction of pyrrolo[1,2-a]quinoxaline derivatives, and the desired products are obtained in moderate yields. In the experiment, the researchers used many compounds, for example, 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Recommanded Product: 2,5-Dimethoxytetrahydrofuran)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Recommanded Product: 2,5-Dimethoxytetrahydrofuran

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Guan, Wen; Zhang, Yunlei; Yan, Changhao; Chen, Yao; Wei, Yanan; Cao, Yu; Wang, Fang; Huo, Pengwei published an article in 2022. The article was titled 《Base-Free Aerobic Oxidation of Furfuralcohols and Furfurals to Furancarboxylic Acids over Nitrogen-Doped Carbon-Supported AuPd Bowl-Like Catalyst》, and you may find the article in ChemSusChem.Recommanded Product: 696-59-3 The information in the text is summarized as follows:

Upgrading furfuralcs. and furfurals to furancarboxylic acids is of great significance for high value-added downstream chems. synthesis and biomass conversion. Developing an efficient catalyst is the key to acquiring a completely sustainable process. Herein, nitrogen-doped carbon-supported bimetallic AuPd bowl-like catalysts were synthesized. The surface wettability of nitrogen-doped carbon was well adjusted by the nitrification process. Benefiting from the alloying effect of bimetallic AuPd catalyst and the formation of hydroxyl radical initiated by H2O dissociation on the hydrophilic surface of nitrated nitrogen-doped carbon, base-free aerobic oxidation of 5-hydroxymethylfurfural (HMF) could produce the highest 2,5-furandicarboxylic acid (FDCA) yield of 93.9%. In-situ IR spectroscopy uncovered adsorption configuration of HMF, and the nitrated carbon surface was favorable for HMF and intermediates to enter the active sites, greatly promoting the catalytic oxidation process. Employing other furfuralcs. (furfuryl alc., furan-2,5-diyldimethanol, 2,5-bishydroxymethylfuran) as well as furfural and 5-methylfurfural as starting materials, 35.6-95.4% yield of furancarboxylic acids (FDCA, 2-furoic acid, 5-methyl-2-furoic acid) were also obtained. Moreover, the developed catalysts could maintain excellent stability and activity after four successive runs. This deep insight into the role of bimetallic synergy and surface wettability provides a basis for the rational design of the highly efficient catalysts for the oxidation of furfuralcs. and furfurals and related reactions. In the experimental materials used by the author, we found 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Recommanded Product: 696-59-3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Recommanded Product: 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Li, Shichen; Lv, Xueyan; Ren, Jianing; Feng, Lei; Ma, Chen published an article in 2022. The article was titled 《A Direct Method for Synthesis of Fluorinated Quinazolinones and Quinoxalines Using Fluorinated Acids without Metals or Additives》, and you may find the article in Synthesis.HPLC of Formula: 696-59-3 The information in the text is summarized as follows:

A direct method using trifluoroacetic acid as a CF3 source for the synthesis of 2-(trifluoromethyl)quinazolin-4-ones and 4-(trifluoromethyl)pyrrolo/indolo[1,2- a]quinoxalines without any catalysts or additives was reported; a wide range of fluorinated compounds were obtained in 52%-94% yield. The results came from multiple reactions, including the reaction of 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3HPLC of Formula: 696-59-3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.HPLC of Formula: 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

In 2022,Guillon, Jean; Savrimoutou, Solene; Albenque-Rubio, Sandra; Pinaud, Noel; Moreau, Stephane; Desplat, Vanessa published an article in Molbank. The title of the article was 《Synthesis, Crystal Structure and Anti-Leukemic Activity of 1,3-Dihydro-1-{1-[4-(4-phenylpyrrolo[1,2-a]quinoxalin-3-yl)benzyl]piperidin-4-yl}-2H-benzimidazol-2-one》.Application of 696-59-3 The author mentioned the following in the article:

Substituted pyrrolo[1,2-a]quinoxaline compound I was synthesized through a multi-step pathway starting from com. available 2-nitroaniline. A structure characterization of compound I was achieved by using FT-IR, 1H-NMR, 13C-NMR, X-Ray and HRMS spectral anal. This new compound I showed an interesting cytotoxic potential against several human leukemia cell lines (HL60, K562 and U937 cells).2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Application of 696-59-3) was used in this study.

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Application of 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Synthetic Route of C6H12O3In 2020 ,《1-phenyl-8-[[4-(pyrrolo[1,2-a]quinoxalin-4-yl)phenyl]methyl]-1,3,8-triazaspiro[4.5]decan-4-one: synthesis, crystal structure and anti-leukemic activity》 appeared in Molbank. The author of the article were Guillon, Jean; Savrimoutou, Solene; Rubio, Sandra; Moreau, Stephane; Pinaud, Noel; Marchivie, Mathieu; Desplat, Vanessa. The article conveys some information:

A multi-step synthesis of 1-phenyl-8-[[4-(pyrrolo[1,2-a]quinoxalin-4-yl)phenyl]methyl]-1,3,8-triazaspiro[4.5]decan4-one using 2-nitroaniline as starting material was reported. Structure characterization of this original pyrrolo[1,2-a]quinoxaline derivative was achieved by FT-IR, 1H-NMR, 13C-NMR, X-Ray and HRMS spectral anal. This title compound showed interesting cytotoxic potential against several human leukemia cell lines (K562, HL60, and U937 cells). The experimental process involved the reaction of 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Synthetic Route of C6H12O3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Synthetic Route of C6H12O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Xin, Xing; Bissett, Amy; Wang, Joyce; Gan, Andrew; Dell, Kiri; Baroutian, Saeid published an article in 2021. The article was titled 《Production of liquid smoke using fluidised-bed fast pyrolysis and its application to green lipped mussel meat》, and you may find the article in Food Control.Reference of 2,5-Dimethoxytetrahydrofuran The information in the text is summarized as follows:

Liquid smoke flavouring as an all-natural food additive is usually prepared by smoldering or a carbonisation method. In this study, liquid smoke was prepared by fast pyrolysis technol. using a fluidised bed reactor with a yield of 30 wt%. GC-MS anal. showed that main functional compounds were furans, carbonyls and phenols. The fast pyrolysis liquid smoke presented a high antioxidant capacity with a total phenolic content of 21.9 mg GAE/mL. Cytotoxicity anal. indicated that it was as safe as com. liquid smoke products. This fast pyrolysis liquid smoke was diluted and applied to treat green lipped mussel meat, and the preserving effects were studied over 30-day refrigerated storage. The microbiol. anal. results showed bacteria growth was inhibited during the first 14 days of the storage period. The image and texture anal. results showed insignificant changes to liquid smoked mussel meat during storage except for color darkening and decreased hardness in meat texture. After reading the article, we found that the author used 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Reference of 2,5-Dimethoxytetrahydrofuran)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Reference of 2,5-Dimethoxytetrahydrofuran

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Li, Ziting; Cui, Shisheng; Yu, Jiayu; Qu, Jiamin; Shi, Jianbing; Tong, Bin; Cai, Zhengxu; Dong, Yuping published an article in 2022. The article was titled 《Amphiphilic and Zwitterionic Multi Arylpyrroles with Near-Infrared Aggregation-Induced Emission for Cell Membrane Imaging》, and you may find the article in ChemNanoMat.Electric Literature of C6H12O3 The information in the text is summarized as follows:

The cell membrane protects the cell stability and balance and participates in various physiol. activities as an exchange channel. Therefore, the real-time monitoring of cell membrane biol. dynamics can help us understand the physiol. state of the current cell. Herein, a type of amphiphilic near IR (NIR) aggregation-induced emission (AIE) mols. was designed and synthesized. Multiarylpyrroles (MAPs) with a dodecyl chain at the 1-position of the pyrrole ring, charged pyridinium sulfonate at the 2,5-position of the pyrrole ring and free rotating aryls at the 3-position of the pyrrole ring can target cell membranes. One of the MAPs, MAP22, had a maximum emission wavelength in the aggregation state of up to 721 nm with a large Stokes shift (∼280 nm). In addition, MAP22 nanoparticles can produce reactive oxygen species (ROS) with a quantum yield of 224%. Therefore, these AIE MAPs are promising candidates for theranostic nanoagents, including NIR fluorescence imaging to target cell membranes and ablate cancer cells by producing ROS. After reading the article, we found that the author used 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Electric Literature of C6H12O3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Electric Literature of C6H12O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

HPLC of Formula: 696-59-3In 2020 ,《A Reductive Supramolecular Hydrogel: A Platform for Facile Fabrication of Diverse Metal-Nanoparticle-Decorated Conductive Networks with Spatiotemporal Control》 appeared in ChemPlusChem. The author of the article were Wang, Peng; He, Guokang; Ji, Jingwei; Li, Jian; Zhou, Kang; Tian, Li; Feng, Kai; Sun, Fuwei; Li, Guangtao. The article conveys some information:

Nanoparticle-hydrogel hybrid composites have a great potential for a broad range of applications, such as antibacterial materials, stimuli-responsive materials and catalysis. A novel supramol. hydrogel system was developed using an amino acid based amphiphile containing a terminal pyrrole moiety as a gelator. The pyrrole moiety could serve as both reducing agent and monomer, and a variety of metal precursors penetrating into the hydrogel could be reduced in situ into metal nanoparticles while the pyrrole moieties preorganized in hydrogel were oxidized into polyprroles, affording metal-nanoparticle-decorated covalent conductive networks. This strategy allows the facile fabrication of diverse mono- or multimetallic nanoparticle-polymer networks from one hydrogel by a simple reaction-diffusion approach. More importantly, besides homogeneous composites, unique multisegment heterogeneous systems with spatiotemporal control were also easily accessible. Furthermore, based on the same multifunctional mol., the fabrication of hierarchically pore-structured metal-nanoparticles-polymers as well as metal-nanoparticles-carbon structures was also realized. In addition to this study using 2,5-Dimethoxytetrahydrofuran, there are many other studies that have used 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3HPLC of Formula: 696-59-3) was used in this study.

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.HPLC of Formula: 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

The author of 《Selective production of acetic acid via catalytic fast pyrolysis of hexoses over potassium salts》 were Kang, Wenyue; Zhang, Zhijun. And the article was published in Catalysts in 2020. Application of 19444-84-9 The author mentioned the following in the article:

Glucose and fructose are widely available and renewable resources. They were used to prepare acetic acid (AA) under the catalysis of potassium acetate (KAc) by thermogravimetric anal. and pyrolysis coupled with gas chromatog. and mass spectrometry. The TGA result showed that the KAc addition lowered the glucose’s thermal decomposition temperatures (about 30°C for initial decomposition temperature and 40°C for maximum mass loss rate temperature), implying its promotion of glucose’s decomposition The Py-GC/MS tests illustrated that the KAc addition significantly altered the composition and distribution of hexose pyrolysis products. The maximum yield of AA was 52.1% for the in situ catalytic pyrolysis of glucose/KAc (1:0.25 wt/wt) mixtures at 350°C for 30 s. Under the same conditions, the AA yield obtained from fructose was 48% and it increased with the increasing amount of KAc. When the ratio reached to 1:1, the yield was 53.6%. In comparison, a study of in situ and online catalytic methods showed that KAc can not only catalyze the primary cracking of glucose, but also catalyze the cracking of a secondary pyrolysis stream. KAc plays roles in both phys. heat transfer and chem. catalysis. The experimental process involved the reaction of 3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9Application of 19444-84-9)

3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9) is a 5-membered cyclic ester. It was obtained via tin-conversion of biomass-derived 1,3-dihydroxyacetone (DHA) and formaldehyde. And it may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis.Application of 19444-84-9

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

《Novel electrochemical sensors from poly[N-(ferrocenyl formacyl) pyrrole]@multi-walled carbon nanotubes nanocomposites for simultaneous determination of ascorbic acid, dopamine and uric acid》 was published in Nanotechnology in 2020. These research results belong to Zhang, Sen; Xu, Feng; Liu, Zhan-Qing; Chen, Ya-Shao; Luo, Yan-Ling. Product Details of 696-59-3 The article mentions the following:

Novel multi-walled carbon nanotubes coated with poly[N-(ferrocenyl formacyl) pyrrole] (MWCNTs@PFFP) nanocomposites were prepared through the in situ oxidation polymerization reaction of N-(ferrocenyl formacyl) pyrrole in the presence of MWCNTs. The MWCNTs@PFFP nanocomposites were characterized by FT-IR, Raman, TGA, XRD, XPS, SEM and TEM techniques. The MWCNTs@PFFP nanocomposites were fabricated into novel electrochem. sensors for simultaneous determination of ascorbic acid (AA), dopamine (DA) and uric acid (UA). The electrochem. behavior of the MWCNTs@PFFP/GCE sensors was examined, and the parameters that influence electrochem. signals were optimized. The exptl. results showed that the fabricated modified electrode sensors exhibited good sensitivity, selectivity, specificity, repeatability and a long lifetime, remaining the initial current of at least 92.5% after 15 days storage in air. The sensors possessed a linear response concentration range over 200-400 muM for AA, 2-16 muM for both DA and UA, and a limit of detection as low as 40.0, 1.1 and 7.3 x 10-1 muM for AA, DA and UA, resp. They are expected to be used as a potential tool for the simultaneous detection of DA, AA and UA in the human body. In the part of experimental materials, we found many familiar compounds, such as 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Product Details of 696-59-3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Product Details of 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem