Ueno, M.; Kitagawa, H.; Ishitani, H.; Yasuda, S.; Hanada, K.; Kobayashi, S. published the artcile< Catalytic enantioselective synthesis of a novel inhibitor of ceramide trafficking, (1R,3R)-N-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl)dodecanamide (HPA-12)>, HPLC of Formula: 137105-97-6, the main research area is HPA12 hydroxyhydroxymethylphenylpropyldodecanamide catalytic enantioselective synthesis ceramide trafficking inhibitor; enantioselective zirconium catalyzed Mannich reaction HPA12 synthesis.
A novel inhibitor of ceramide trafficking, (1R,3R)-N-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl)dodecanamide (HPA-12, I), has been synthesized using a chiral zirconium-catalyzed asym. Mannich-type reaction as a key-step.
Tetrahedron Letters published new progress about Mannich reaction (enantioselective zirconium-catalyzed). 137105-97-6 belongs to class tetrahydrofurans, and the molecular formula is C9H15NO4, HPLC of Formula: 137105-97-6.
Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem