Ren, Fei; Li, Zeshun; Li, Kai; Zheng, Xiaoyan; Shi, Jianbing; Zhang, Chen; Guo, Heng; Tong, Bin; Xi, Lei; Cai, Zhengxu; Dong, Yuping published an article in 2021. The article was titled 《Donor strategy for promoting nonradiative decay to achieve an efficient photothermal therapy for treating cancer》, and you may find the article in Science China: Chemistry.Quality Control of 2,5-Dimethoxytetrahydrofuran The information in the text is summarized as follows:
Photothermal therapy (PTT) is emerging as an effective treatment for superficial carcinoma. A key challenge to the effectiveness of PTT is to develop photosensitizers with high photothermal conversion efficiency. Aiming to address this challenge, we develop a series of multi-arylpyrrole derivatives with different donors that contain different multi-rotor structures to explore PTT photosens/itizers of high efficiency. Among these multi-arylpyrrole derivatives, MAP4-FE nanoparticles with a small size of their donor groups and better-donating ability exhibit a high photothermal conversion efficiency (up to 72%) when it is encapsulated by an amphiphilic polymer. As a result, the MAP4-FE nanoparticles have shown satisfactory PTT effects on in vivo tumor eradication under the guidance of photoacoustic signals. The findings of this study provide significant insights for the development of high-efficiency PTT photosensitizers for cancer treatment by making full use of the nonradiative decay of small size donors as rotors. After reading the article, we found that the author used 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Quality Control of 2,5-Dimethoxytetrahydrofuran)
2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Quality Control of 2,5-Dimethoxytetrahydrofuran
Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem