The author of 《Design, synthesis, and evaluation of the antimycobacterial activity of 3-mercapto-1,2,4-triazole-pyrrole hybrids》 were Roman, Gheorghe; Bostanaru, Andra-Cristina; Nastasa, Valentin; Mares, Mihai. And the article was published in Turkish Journal of Chemistry in 2019. Quality Control of 2,5-Dimethoxytetrahydrofuran The author mentioned the following in the article:
A series of 3-mercapto-1,2,4-triazole-pyrrole hybrids was designed as antimycobacterial agents by employing 5-(4-(1H-pyrrol-1-yl)phenyl)-4H-1,2,4-triazole-3-thiol as the scaffold onto which several types of moieties were introduced in the triazole ring at N-4 and N-2 and as substituents of the mercapto function. The aforementioned moieties are an allyl or a Ph moiety at N-4; an aminomethyl group at N-2; or Me, substituted benzyl, ethoxycarbonylmethyl, or substituted phenacyl at sulfur. Investigation of the compounds in the resulting library as growth inhibitors of Mycobacterium smegmatis showed that their min. inhibitory concentration was higher than 64 mg/L. The experimental process involved the reaction of 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Quality Control of 2,5-Dimethoxytetrahydrofuran)
2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Quality Control of 2,5-Dimethoxytetrahydrofuran
Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem