Day: October 13, 2022

Cao, Peng; Lin, Lu; Qi, Haifeng; Chen, Rui; Wu, Zhijie; Li, Ning; Zhang, Tao; Luo, Wenhao published the artcile< Zeolite-Encapsulated Cu Nanoparticles for the Selective Hydrogenation of Furfural to Furfuryl Alcohol>, Electric Literature of 97-99-4, the main research area is zeolite encapsulated copper nanoparticle hydrogenation furfural furfuryl alc.

Catalytic hydrogenation of furfural (FFL) to furfuryl alc. (FAL) is one of the pivotal reactions for biomass valorization. Herein, well-defined Cu nanoparticles of ~1.8 nm encapsulated within titanium silicalite-1 (TS-1) have been successfully prepared by an in situ encapsulation approach, which possesses significant advantages in metal dispersion and uniformity compared to the traditional wet impregnation method. After a Na ion-exchange process for modulation of the zeolite microenvironment, the obtained Na-Cu@TS-1 catalyst affords an enhanced activity and selectivity in the selective hydrogenation of FFL into FAL, with a FFL conversion of 93.0% and a FAL selectivity of 98.1% at 110°C, 10 bar H2, after a reaction time of 2 h. A turnover frequency value of 55.2 h-1 has been achieved, reflecting some of the highest activity for Cu-based heterogeneous catalysts under similar conditions. Comprehensive characterization studies reveal that the confined environment of the zeolite could not only provide the spatial restriction for metal particles but also induce an electronic interaction between encapsulated Cu nanoparticles and Ti species in Na-Cu@TS-1, which both lead to effective suppression of the metal aggregation and leaching during catalysis. Na species, added by the ion exchange, not only mediate the acid/basic property of the zeolite for suppressing the side reactions but also modulate the encapsulated Cu species into an electronic-rich state, facilitating the FFL hydrogenation. Deactivation of Na-Cu@TS-1 is primarily caused by Na leaching into the liquid phase, but activity can be almost restored after a Na readdn. process.

ACS Catalysis published new progress about Adsorption. 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, Electric Literature of 97-99-4.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Latini, Alessandra; Orsini, Diego; Ambrifi, Marina; Colafigli, Manuela; Zaccarelli, Mauro; Cristaudo, Antonio published the artcile< Classical Kaposi's sarcoma concurrent with ledipasvir-sofosbuvir therapy for hepatitis C infection.>, Electric Literature of 58-97-9, the main research area is .

There is no abstract available for this document.

Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia published new progress about 58-97-9. 58-97-9 belongs to class tetrahydrofurans, and the molecular formula is C9H13N2O9P, Electric Literature of 58-97-9.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Wang, Chunhua; Wang, Anjie; Yu, Zhiquan; Wang, Yao; Sun, Zhichao; Kogan, Victor M.; Liu, Ying-Ya published the artcile< Aqueous phase hydrogenation of furfural to tetrahydrofurfuryl alcohol over Pd/UiO-66>, Quality Control of 97-99-4, the main research area is hydrogenation furfural tetrahydrofurfuryl palladium catalyst.

A Pd/UiO-66 catalyst was synthesized with well-dispersed Pd nanoparticles. The obtained catalyst was tested in the hydrogenation of furfural to tetrahydrofurfuryl alc. in various solvents, Water was the most suitable solvent. Pd/UiO-66 exhibited much higher activity than Pd/SiO2 and Pd/γ-Al2O3, completely converting furfural to tetrahydrofurfuryl alc. with 100% selectivity under mild conditions. The hydrogenation of C=O moiety in tetrahydrofurfural was rate-determining step. Static adsorption measurement indicated that the adsorption of furfural on UiO-66 was significantly stronger than that on SiO2 or γ-Al2O3, suggesting that the adsorption play an important role in the gas-liquid-solid furfural hydrogenation reaction.

Catalysis Communications published new progress about Catalyst supports. 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, Quality Control of 97-99-4.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Gao, Guoming; Shao, Yuewen; Gao, Yong; Wei, Tao; Gao, Guanggang; Zhang, Shu; Wang, Yi; Chen, Qifeng; Hu, Xun published the artcile< Synergetic effects of hydrogenation and acidic sites in phosphorus-modified nickel catalysts for the selective conversion of furfural to cyclopentanone>, Recommanded Product: (Tetrahydrofuran-2-yl)methanol, the main research area is synergetic hydrogenation acidic phosphorus nickel catalyst furfural cyclopentanone.

Cyclopentanone (CPO) is a value-added chem. that can be produced from furfural via hydrogenation coupled with an acid-catalysis step. Developing an effective bi-functional catalyst remains a challenge to be overcome. In this study, phosphorus was introduced to Ni/Al2O3 to modify the distribution of acidic sites and to tailor the activity of the metal sites for hydrogenation, with the aim of developing an active and cost-effective transition-metal-based catalyst for the conversion of furfural to CPO. The results showed that phosphorus species could react with both alumina and metallic nickel, forming an AlPO4 phase and nickel phosphide species. The formation of the AlPO4 phase reduced the specific area of the catalyst and increased the abundance of acidic sites. The formation of nickel phosphide species (Ni2P, Ni3P, and Ni12P5) tailored the selectivity of the hydrogenation sites. Furfural was only hydrogenated to furfuryl alc. (FA), while further hydrogenation to tetrahydrofurfuryl alc. (TFA) was inhibited. The introduced acidic sites further catalyzed the conversion of the formed FA to CPO. The balanced distribution of the hydrogenation sites and the acidic sites, as well as their tailored activity for hydrogenation and acid-catalyzed reactions, was crucial for the selective conversion of furfural to CPO.

Catalysis Science & Technology published new progress about Acid catalysis. 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, Recommanded Product: (Tetrahydrofuran-2-yl)methanol.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Delima, Roxanna S.; Stankovic, Mia D.; MacLeod, Benjamin P.; Fink, Arthur G.; Rooney, Michael B.; Huang, Aoxue; Jansonius, Ryan P.; Dvorak, David J.; Berlinguette, Curtis P. published the artcile< Selective hydrogenation of furfural using a membrane reactor>, Recommanded Product: (Tetrahydrofuran-2-yl)methanol, the main research area is furfural selective hydrogenation membrane reactor.

Electrocatalytic palladium membrane reactors (ePMRs) use electricity and water to drive hydrogenation reactions without forming H2 gas. In these reactors, a hydrogen-permeable palladium foil phys. separates electrochem. proton generation in aqueous media from chem. hydrogenation in organic media. The authors report herein the use of the ePMR to electrolytically hydrogenate furfural, an important biomass derivative This system was proven to convert furfural into furfuryl alc. and tetrahydrofurfuryl alc. with 84% and 98% selectivities, resp. To reach these high selectivities, the authors designed and built an ePMR for high-throughput testing. Using this apparatus, the authors tested how different solvents, catalysts, and applied currents impacted furfural hydrogenation. The authors found that bulky solvents with weak nucleophilicities suppressed the formation of side products. Notably, these types of solvents are not compatible with standard electrochem. hydrogenation architectures where electrolysis and hydrogenation occur in the same reaction chamber. This work highlights the utility of the ePMR for selective furfural hydrogenation without H2 gas, and presents a possible pathway for helping to decarbonize the hydrogenation industry.

Energy & Environmental Science published new progress about Hydrogenation catalysts. 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, Recommanded Product: (Tetrahydrofuran-2-yl)methanol.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Zhao, Baihua; Wen, Lieming; Liu, Dan; Huang, Shanya published the artcile< The Visualized Urethral Mobility Profile in Stress Urinary Incontinence Described by Four-Dimensional Transperineal Ultrasound.>, Related Products of 58-97-9, the main research area is cough stress test; pelvic floor ultrasound; stress urinary incontinence; urethral hypermobility; urethral mobility profile.

OBJECTIVES: To describe the urethral mobility during urine leaking in stress urinary incontinence (SUI) by transperineal ultrasound (TPUS) with urethral mobility profile (UMP) analysis. METHODS: This was a prospective study of 380 women who had a cough stress test (CST) with TPUS. UMP software automatically placed six equidistant points from the bladder neck (Point 1) to the external urethral meatus (Point 6) and determined their x and y coordinates relative to the symphysis pubis. Urethral mobility vector of Points 1-6 (Vectors 1-6) and the distance between the six points and the symphysis (Dist. 1-6) were calculated and compared between the two groups. The visualized UMP was created by reproducing the positions of the six points at rest and on Valsalva. RESULTS: Valid data of 188 women with SUI and 174 continent women were analyzed. The mean age of all 362 women was 49.3 years. Mean body mass index in the SUI group was significantly increased (23.8 vs 22.2 kg/m2 , P < .001). During CST, Vectors 1-6 and Dist. 2-6 were significantly increased (all P < .005) in the SUI group. The UMP showed the mid-urethral rotated down around the symphysis pubis. The upper urethral profile in the two groups was similar. But the gap between the mid-urethra and the symphysis was wider in the SUI group. CONCLUSIONS: The visualized UMP illustrated the mid-urethral hypermobility in SUI by showing a wider gap due to the unstable connection between the mid-urethra and the symphysis pubis. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine published new progress about 58-97-9. 58-97-9 belongs to class tetrahydrofurans, and the molecular formula is C9H13N2O9P, Related Products of 58-97-9.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Kumar, Abhinav; Shivhare, Atal; Bal, Rajaram; Srivastava, Rajendra published the artcile< Metal and solvent-dependent activity of spinel-based catalysts for the selective hydrogenation and rearrangement of furfural>, Recommanded Product: (Tetrahydrofuran-2-yl)methanol, the main research area is furfural nickel copper metal catalyst hydrogenation rearrangement.

The development of cost-effective heterogeneous catalysts for the selective conversion of biomass-derived platform chems. into value-added chems. and liquid fuels will pave the way towards the development of sustainable biorefineries. Herein, we perform in-depth optimization of the catalyst composition and exptl. conditions to selectively produce three important value-added chems. from furfural, including cyclopentanone, furfuryl alc., and tetrahydrofurfuryl alc. Results show that the Ni(10%)/CuFe2O4 catalyst affords cyclopentanone as a major product with >90% selectivity in water at 423 K and 1 MPa H2. Meanwhile, switching to non-aqueous solvents, including hexane, isopropanol, toluene, and ethanol, selectively produces tetrahydrofurfuryl alc. as a major product under identical reaction conditions. Over the Cu(10%)/CuFe2O4 catalyst, furfuryl alc. is produced as a major product in water at 393 K and 1 MPa H2. Control experiments over M/CuO, M/Fe3O4, and M/SBA-15 catalysts are also performed; however. these catalysts afford much lower conversion compared to the M/CuFe2O4 catalysts due to the higher Lewis acidity of the CuFe2O4 support. The physicochem. properties of these catalysts are characterized using powder XRD, HR-TEM, XPS, and pyridine FT-IR. Finally, based on the existing literature, plausible reaction mechanisms for the production of cyclopentanone, tetrahydrofurfuryl alc., and furfural alc. on M/CuFe2O4 catalysts are proposed. The present work provides insight into the development of cost-effective and efficient catalysts for the valorization of furfural under mild conditions.

Sustainable Energy & Fuels published new progress about Acidity. 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, Recommanded Product: (Tetrahydrofuran-2-yl)methanol.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Shao, Yuewen; Guo, Mingzhu; Wang, Junzhe; Sun, Kai; Zhang, Lijun; Zhang, Shu; Hu, Guangzhi; Xu, Leilei; Yuan, Xiangzhou; Hu, Xun published the artcile< Selective Conversion of Furfural into Diols over Co-Based Catalysts: Importance of the Coordination of Hydrogenation Sites and Basic Sites>, Category: tetrahydrofurans, the main research area is selective hydrogenation furfural diol Cobalt magnesium aluminum hydrogenation catalyst.

1,5-Pentanediol (1,5-PDO) is a feedstock for synthesis of polyesters and polyurethanes, and its selective production from furfural is a desirable route but very challenging. In this study, the production of 1,5-PDO from furfural was investigated over the Co-Mg-Al catalyst, containing abundant hydrogenation sites and basic sites. Using layered double hydroxides as the catalyst precursor benefited dispersion of metallic Co particles via preventing migration of cobalt species and developing pore structures. Furthermore, the Co-Mg-Al catalyst possessed abundant basic sites, rendering its superior catalytic activity to Co-Al or Co-Mg catalysts. In situ diffuse reflectance IR spectroscopy (DRIFTS) characterization for FA conversion demonstrated that the cooperation of abundant hydrogenation sites and basic sites facilitated a strong adsorption of C-O-C and carbon-carbon double-bond groups, which benefited the conversion of FA into diols.

Industrial & Engineering Chemistry Research published new progress about Glycols Role: SPN (Synthetic Preparation), PREP (Preparation). 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, Category: tetrahydrofurans.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Eckman, Mark H; Woodle, E Steve; Thakar, Charuhas V; Alloway, Rita R; Sherman, Kenneth E published the artcile< Cost-effectiveness of Using Kidneys From HCV-Viremic Donors for Transplantation Into HCV-Uninfected Recipients.>, Related Products of 58-97-9, the main research area is End-stage kidney disease (ESKD); cost-effectiveness analysis; decision analysis; direct-acting agent (DAA); glecaprevir; healthcare cost; hepatitis C; kidney transplantation; medical decision making; pibrentasvir; quality-of-life (QOL); transplant waiting list.

RATIONALE & OBJECTIVE: Less than 4% of patients with kidney failure receive kidney transplants. Although discard rates of hepatitis C virus (HCV)-viremic kidneys are declining, ~39% of HCV-viremic kidneys donated between 2018 and 2019 were discarded. Highly effective antiviral agents are now available to treat chronic HCV infection. Thus, our objective was to examine the cost-effectiveness of transplanting kidneys from HCV-viremic donors into HCV-uninfected recipients. STUDY DESIGN: Markov state transition decision model. Data sources include Medline search results, bibliographies from relevant English language articles, Scientific Registry of Transplant Recipients, and the US Renal Data System. SETTING & POPULATION: US patients receiving maintenance hemodialysis who are on kidney transplant waiting lists. INTERVENTION(S): Transplantation with an HCV-unexposed kidney versus transplantation with an HCV-viremic kidney and HCV treatment. OUTCOMES: Effectiveness measured in quality-adjusted life-years and costs measured in 2018 US dollars. MODEL, PERSPECTIVE, AND TIMEFRAME: We used a health care system perspective with a lifelong time horizon. RESULTS: In the base-case analysis, transplantation with an HCV-viremic kidney was more effective and less costly than transplantation with an HCV-unexposed kidney because of the longer waiting times for HCV-unexposed kidneys, the substantial excess mortality risk while receiving dialysis, and the high efficacy of direct-acting antiviral agents for HCV infection. Transplantation with an HCV-viremic kidney was also preferred in sensitivity analyses of multiple model parameters. The strategy remained cost-effective unless waiting list time for an HCV-viremic kidney exceeded 3.1 years compared with the base-case value of 1.56 year. LIMITATIONS: Estimates of waiting times for patients willing to accept an HCV-viremic kidney were based on data for patients who received HCV-viremic kidney transplants. CONCLUSIONS: Transplanting kidneys from HCV-viremic donors into HCV-uninfected recipients increased quality-adjusted life expectancy and reduced costs compared with a strategy of transplanting kidneys from HCV-unexposed donors.

American journal of kidney diseases : the official journal of the National Kidney Foundation published new progress about 58-97-9. 58-97-9 belongs to class tetrahydrofurans, and the molecular formula is C9H13N2O9P, Related Products of 58-97-9.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Yang, Acong; Bofill-De Ros, Xavier; Stanton, Ryan; Shao, Tie-Juan; Villanueva, Patricia; Gu, Shuo published the artcile< TENT2, TUT4, and TUT7 selectively regulate miRNA sequence and abundance>, Category: tetrahydrofurans, the main research area is .

Abstract: TENTs generate miRNA isoforms by 3′ tailing. However, little is known about how tailing regulates miRNA function. Here, we generate isogenic HEK293T cell lines in which TENT2, TUT4 and TUT7 are knocked out individually or in combination. Together with rescue experiments, we characterize TENT-specific effects by deep sequencing, Northern blot and in vitro assays. We find that 3′ tailing is not random but highly specific. In addition to its known adenylation, TENT2 contributes to guanylation and uridylation on mature miRNAs. TUT4 uridylates most miRNAs whereas TUT7 is dispensable. Removing adenylation has a marginal impact on miRNA levels. By contrast, abolishing uridylation leads to dysregulation of a set of miRNAs. Besides let-7, miR-181b and miR-222 are neg. regulated by TUT4/7 via distinct mechanisms while the miR-888 cluster is upregulated specifically by TUT7. Our results uncover the selective actions of TENTs in generating 3′ isomiRs and pave the way to investigate their functions.

Nature Communications published new progress about 58-97-9. 58-97-9 belongs to class tetrahydrofurans, and the molecular formula is C9H13N2O9P, Category: tetrahydrofurans.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem