Bergman, Ylva; Ciampini, Marisa; Jalal, Sania; Lagiakos, Helen Rachel; Aguilar, Marie-Isabel; Perlmutter, Patrick published the artcile< The synthesis of Fmoc-O-allyl β-serine>, Related Products of 137105-97-6, the main research area is serine beta allyl Fmoc protected synthesis diazomethane safety; allyl serine Boc protected Arndt Eistert homologation Seebach safety; aspartic acid tertbutoxycarbonyl protected allylation.
Two concise routes for the synthesis of the title amino acid have been developed. The first route employs Seebach’s general approach with Arndt Eistert homologation of Boc-O-allyl α-serine (Boc = tert-butoxycarbonyl) as the key process. The second route employs an approach using Boc-α-aspartic acid as a starting material with a selective palladium-catalyzed O-allylation as key processes. These two routes are evaluated for their relative efficiency and safety.
Tetrahedron: Asymmetry published new progress about Allylation. 137105-97-6 belongs to class tetrahydrofurans, and the molecular formula is C9H15NO4, Related Products of 137105-97-6.
Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem