《Synthesis, characterization and antimicrobial evaluation of some 1,2,4-triazolo-5-thione derivatives》 was written by Singh, Gurdeep; Jain, Neetesh K.; Sahu, Kiran. Application of 696-59-3This research focused ontriazolothione preparation antibacterial activity. The article conveys some information:
In this study, substituted 1,2,4-triazolo-5-thione derivatives I (R = 4-nitro, 3-nitro; R1 = Ph, Et, Me;) were synthesized from substituted aromatic aldehydes C6H4CHO, and succinic acid and the structure of synthesized compounds were established by physicochem. (M.p., Rf value) and spectral anal. The title compounds were then evaluated for their antimicrobial activity against ciprofloxacin as a standard drug using agar plate method. The synthesized derivatives I (R = 3-nitro, R1 = Et; R = 3-nitro, R1 = Me) were found to possess very promising antimicrobial activity. In addition to this study using 2,5-Dimethoxytetrahydrofuran, there are many other studies that have used 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Application of 696-59-3) was used in this study.
2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Application of 696-59-3
Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem