Product Details of 696-59-3In 2021 ,《Synthesis and Characterization of New S-substituted Sulfanylpyridines, 3-Aminothieno[2,3-b] Pyridines and 3-(1H-pyrrol-1-yl) Thieno[2,3-b] Pyridines and Related Heterocycles》 was published in Journal of Chemical and Pharmaceutical Research. The article was written by Bakhite, Etify. The article contains the following contents:
Reaction of Et (3-cyano-5-ethoxycarbonyl-6-methyl-4-styryl-2-pyridylsulfanyl)acetate with hydrazine hydrate gave a mixture of the corresponding (3-cyano-5-ethoxycarbonyl-6-methyl-4-styryl-2-pyridylsulfanyl)acetohydrazide and di-Et 3-amino-6-methyl-4-styrylthieno[2,3-b]pyridine-2,5-dicarboxylate. The latter compound was reacted with 2,5-dimethoxytetrahydrofuran to give 3-(1H-pyrrol-1-yl)thieno[2,3-b]pyridine. Partial hydrazinolysis resulted in the formation of 5-ethoxycarbonyl-6-methyl-3-(1H-pyrrol-1-yl)-4-styrylthieno[2,3-b]pyridine-2-carbohydrazide. The (3-cyano-5-ethoxycarbonyl-6-methyl-4-styryl-2-pyridylsulfanyl)acetohydrazide and 5-ethoxycarbonyl-6-methyl-3-(1H-pyrrol-1-yl)-4-styrylthieno[2,3-b]pyridine-2-carbohydrazide were used as precursors for the title compounds, e.g., I by subjecting them to some sequential reactions with different reagents. All new compounds were characterized on the basis of their elemental analyses and spectroscopic data. In the part of experimental materials, we found many familiar compounds, such as 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Product Details of 696-59-3)
2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Product Details of 696-59-3
Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem