Alvarez, Alejandro; Gutierrez, Alejandra; Ramirez, Cristina; Cuenca, Frank; Bolivar, German published an article on January 31 ,2022. The article was titled 《Aroma compounds produced by liquid fermentation with Saccharomyces cerevisiae and Zygosaccharomyces rouxii from castor oil through cell permeabilization》, and you may find the article in Biocatalysis and Agricultural Biotechnology.COA of Formula: C4H6O3 The information in the text is summarized as follows:
The use of microorganisms to produce aroma mols. is growing in the flavor and fragrance industries due to the increased market for natural products. In this study, the effect of the type of microorganism, and cellular permeabilization on the production of aroma mols. from castor oil by liquid fermentation with yeasts, was assessed for possible application in the production of natural flavors. Different treatments were assessed with a three-way factorial design (type of microorganism, cell permeabilization and amount of castor oil), the aroma profile was analyzed using gas chromatog. with mass spectrometry (GC-MS), and the treatments were classified by principal component anal. (PCA). The results showed a significant effect of the yeast S. cerevisiae and Z. rouxii, the permeabilization treatment, and the amount of castor oil in the production of aroma compounds (p < 0.05). The mols. 4-hydroxy-2-pentenoic acid γ-lactone, Me pyruvate, 2,3,4-trimethyl-3-pentanol, and δ-decalactone were affected by all the factors. The production of metabolites increased with the permeabilization treatments for certain mols. like ethanol and organic acids, whereas the generation of others decreased. The use of these microorganisms and cell permeabilization are promising approaches for producing mols. with applications in natural flavors. In addition to this study using 3-Hydroxydihydrofuran-2(3H)-one, there are many other studies that have used 3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9COA of Formula: C4H6O3) was used in this study.
3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9) is a 5-membered cyclic ester. It was obtained via tin-conversion of biomass-derived 1,3-dihydroxyacetone (DHA) and formaldehyde. And it may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis.COA of Formula: C4H6O3
Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem