Guo, Yu; Wang, Ruo-Ya; Kang, Jia-Xin; Ma, Yan-Na; Xu, Cong-Qiao; Li, Jun; Chen, Xuenian published an article about the compound: Methyl 6-bromonicotinate( cas:26218-78-0,SMILESS:C1=NC(=CC=C1C(=O)OC)Br ).Electric Literature of C7H6BrNO2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:26218-78-0) through the article.
Authors report here a facile synthesis method of primary and secondary amides through a direct amidation of esters with sodium amidoboranes (NaNHRBH3, R = H, Me), at room temperature without using catalysts and other reagents. This process is rapid and chemoselective, and features quant. conversion and wide applicability for esters tolerating different functional groups. The exptl. and theor. studies reveal a reaction mechanism with nucleophilic addition followed by a swift proton transfer-induced elimination reaction.
This compound(Methyl 6-bromonicotinate)Electric Literature of C7H6BrNO2 was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem